Literature DB >> 21823589

Current status and research strategies in tuberculosis drug development.

Lynn G Dover1, Geoffrey D Coxon.   

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Year:  2011        PMID： 21823589     DOI： 10.1021/jm200305q

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  12 in total

1.  Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan.

Authors:  Robert W Wheatley; Ruixiang Blake Zheng; Michele R Richards; Todd L Lowary; Kenneth K S Ng
Journal:  J Biol Chem       Date:  2012-06-15       Impact factor: 5.157

2.  Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis.

Authors:  V V N Phani Babu Tiruveedhula; Christopher M Witzigmann; Ranjit Verma; M Shahjahan Kabir; Marc Rott; William R Schwan; Sara Medina-Bielski; Michelle Lane; William Close; Rebecca L Polanowski; David Sherman; Aaron Monte; Jeffrey R Deschamps; James M Cook
Journal:  Bioorg Med Chem       Date:  2013-10-21       Impact factor: 3.641

Review 3.  Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action.

Authors:  Katherine A Sacksteder; Marina Protopopova; Clifton E Barry; Koen Andries; Carol A Nacy
Journal:  Future Microbiol       Date:  2012-07       Impact factor: 3.165

4.  The expression of ABC efflux pump, Rv1217c-Rv1218c, and its association with multidrug resistance of Mycobacterium tuberculosis in China.

Authors:  Ke Wang; Hao Pei; Biao Huang; Xue Zhu; Jue Zhang; Bin Zhou; Lan Zhu; Yi Zhang; Fan-Fan Zhou
Journal:  Curr Microbiol       Date:  2012-11-11       Impact factor: 2.188

5.  Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies.

Authors:  Ramkishore Matsa; Parameshwar Makam; Guneswar Sethi; Ahammed Ameen Thottasseri; Aswani Raj Kizhakkandiyil; Krishna Ramadas; Vignesh Mariappan; Agieshkumar Balakrishna Pillai; Tharanikkarasu Kannan
Journal:  RSC Adv       Date:  2022-06-22       Impact factor: 4.036

6.  Evaluation of pseudopteroxazole and pseudopterosin derivatives against Mycobacterium tuberculosis and other pathogens.

Authors:  Malcolm W B McCulloch; Brad Haltli; Douglas H Marchbank; Russell G Kerr
Journal:  Mar Drugs       Date:  2012-08-15       Impact factor: 6.085

Review 7.  Combating Tuberculosis Infection: A Forbidding Challenge.

Authors:  Tejal Rawal; Shital Butani
Journal:  Indian J Pharm Sci       Date:  2016 Jan-Feb       Impact factor: 0.975

8.  Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.

Authors:  Colin R Wilson; Richard K Gessner; Atica Moosa; Ronnett Seldon; Digby F Warner; Valerie Mizrahi; Candice Soares de Melo; Sandile B Simelane; Aloysius Nchinda; Efrem Abay; Dale Taylor; Mathew Njoroge; Christel Brunschwig; Nina Lawrence; Helena I M Boshoff; Clifton E Barry; Frederick A Sirgel; Paul van Helden; C John Harris; Richard Gordon; Sonja Ghidelli-Disse; Hannah Pflaumer; Markus Boesche; Gerard Drewes; Olalla Sanz; Gracia Santos; Maria José Rebollo-Lopez; Beatriz Urones; Carolyn Selenski; Maria Jose Lafuente-Monasterio; Matthew Axtman; Joël Lelièvre; Lluis Ballell; Rudolf Mueller; Leslie J Street; Sandeep R Ghorpade; Kelly Chibale
Journal:  J Med Chem       Date:  2017-12-07       Impact factor: 7.446

9.  Structural Simplification of Bedaquiline: the Discovery of 3-(4-(N,N-Dimethylaminomethyl)phenyl)quinoline-Derived Antitubercular Lead Compounds.

Authors:  Chunxian He; Laura Preiss; Bin Wang; Lei Fu; Hui Wen; Xiang Zhang; Huaqing Cui; Thomas Meier; Dali Yin
Journal:  ChemMedChem       Date:  2016-10-28       Impact factor: 3.466

10.  Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity.

Authors:  Jessica N Akester; Paul Njaria; Aloysius Nchinda; Claire Le Manach; Alissa Myrick; Vinayak Singh; Nina Lawrence; Mathew Njoroge; Dale Taylor; Atica Moosa; Anthony J Smith; Elizabeth J Brooks; Anne J Lenaerts; Gregory T Robertson; Thomas R Ioerger; Rudolf Mueller; Kelly Chibale
Journal:  ACS Infect Dis       Date:  2020-06-15       Impact factor: 5.084
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