Literature DB >> 21822907

Three Dimensional Power Doppler evaluation of human endometrium after administration of oxytocine receptor antagonist (OTRa) in an IVF program.

Konstantinos Kalmantis1, Dimitrios Loutradis, Elias Lymperopoulos, Panagiotis Beretsos, Ritsa Bletsa, Aris Antsaklis.   

Abstract

PURPOSE: To compare endometrial and subendometrial morphological changes and vascularity as measured by 3D Power Doppler sonography, based on a specific scoring system between women subjected or not to oxytocine receptor antagonist (OTRa) during IVF cycles.
METHODS: Twenty-six women were divided into groups according to OTRa (Atosiban tractocide) administration. The first group (control n = 13 women) was examined with 3D Power Doppler 3 days after embryo transfer. The second group (n = 13 women) was administered 7.5 mg intravenous tractocide 2 days after embryo transfer and a 3D Power Doppler was performed after a day.
RESULTS: The control group presented the following ultrasonographic characteristics: (a) echogenic endometrium in all cases, (b) endometrial thickness >7 mm in all cases (84.6%), (c) endometrial volume >2.31 cm(3) in 5 cases (38.5%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 6 cases (46.2%) and (f) complex vessel's architecture in 2 cases (15.4%). In women who underwent OTRa administration were observed: (a) echogenic endometrium in 1 case (7.7%), triple line endometrium in 12 cases (92.3%), (b) endometrial thickness >7 mm in all cases, (c) endometrial volume >2.31 cm(3) in 11 cases (84.6%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 11 cases (84.6%) and (f) complex vessel's architecture in 6 cases (46.2%).
CONCLUSIONS: Women who have taken OTRa presented an endometrium with characteristics more predictive of implantation.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21822907     DOI: 10.1007/s00404-011-2019-2

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  3 in total

Review 1.  Oxytocin antagonists for assisted reproduction.

Authors:  Laurentiu Craciunas; Nikolaos Tsampras; Martina Kollmann; Nick Raine-Fenning; Meenakshi Choudhary
Journal:  Cochrane Database Syst Rev       Date:  2021-09-01

2.  Efficacy of oxytocin antagonist infusion in improving in vitro fertilization outcomes on the day of embryo transfer: A meta-analysis.

Authors:  Seul Ki Kim; E-Jung Han; Sun Mie Kim; Jung Ryeol Lee; Byung Chul Jee; Chang Suk Suh; Seok Hyun Kim
Journal:  Clin Exp Reprod Med       Date:  2016-12-26

3.  A Prospective Case-control Trial to Evaluate and Compare the Efficacy and Safety of Atosiban versus Placebo in In vitro Fertilization-embryo Transfer Program.

Authors:  Vineet Mishra; Himani Agarwal; Sugandha Goel; Priyankur Roy; Sumesh Choudhary; Sunita Lamba
Journal:  J Hum Reprod Sci       Date:  2018 Apr-Jun
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.