Literature DB >> 21821414

Synthesis and antioxygenic activities of seabuckthorn flavone-3-ols and analogs.

N Pandurangan1, Chinchu Bose, A Banerji.   

Abstract

A practical synthesis of polyhydroxy- and regiospecifically methylated flavone-3-ols which are components of commercial 'seabuckthorn flavone' has been achieved by modified Algar-Flynn-Oyamada method. Antioxidant activities of seabuckthorn extracts, isolated products and a number of flavone-3-ols have been determined. Structure-activity relationships have been discussed. Amongst the compounds tested, gallic acid, which is also present in seabuckthorn, was found to be the most effective antioxidant and radioprotectant.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21821414     DOI： 10.1016/j.bmcl.2011.07.008

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents.

Authors:  Xing Zhang; Omar Khalidi; So Young Kim; Ruitong Wang; Victor Schultz; Brady F Cress; Richard A Gross; Mattheos A G Koffas; Robert J Linhardt
Journal:  Bioorg Med Chem Lett       Date:  2016-05-04       Impact factor: 2.823

2.  6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells.

Authors:  Xing Wang; Zhiwei Wang; Preetpal Singh Sidhu; Umesh R Desai; Qibing Zhou
Journal:  PLoS One       Date:  2015-03-19       Impact factor: 3.240

3.  Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression.

Authors:  Hiroaki Eguchi; Toshiyuki Matsunaga; Satoshi Endo; Kenji Ichihara; Akira Ikari
Journal:  Nutrients       Date:  2020-04-23       Impact factor: 5.717

4.  Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study.

Authors:  Ujjal Das; Sushobhan Biswas; Sreya Chattopadhyay; Anindita Chakraborty; Rakhi Dey Sharma; Asoke Banerji; Sanjit Dey
Journal:  Sci Rep       Date:  2017-10-25       Impact factor: 4.379
  4 in total

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