Literature DB >> 2182070

Non-medicinal ingredients.

A W Scott1.   

Abstract

Many drug products contain excipients which perform important functions in terms of stability, solubility and identification. Excipients should not be considered as inactive ingredients, as they have been associated with a wide range of adverse reactions in some individuals. Monitoring for excipient toxicity is important. Equally important, is the provision of non-medicinal ingredient information on packaging, patient information leaflets and prescribing information, as most excipient-related toxicity is preventable when the formulation is known.

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Year:  1990        PMID: 2182070     DOI: 10.2165/00002018-199000051-00015

Source DB:  PubMed          Journal:  Drug Saf        ISSN: 0114-5916            Impact factor:   5.606


  8 in total

1.  Spontaneous reporting of adverse drug reactions. II: Uses.

Authors:  M D Rawlins
Journal:  Br J Clin Pharmacol       Date:  1988-07       Impact factor: 4.335

2.  Spontaneous reporting of adverse drug reactions. I: the data.

Authors:  M D Rawlins
Journal:  Br J Clin Pharmacol       Date:  1988-07       Impact factor: 4.335

3.  Dermatitis due to formaldehyde-releasing agents in cosmetics and medicaments.

Authors:  A A Fisher
Journal:  Cutis       Date:  1978-12

4.  Cyclosporin encephalopathy associated with fat embolism induced by the drug's solvent.

Authors:  W A Hoefnagels; E J Gerritsen; O F Brouwer; J H Souverijn
Journal:  Lancet       Date:  1988-10-15       Impact factor: 79.321

5.  Paradoxical deterioration in lung function after nebulised salbutamol in wheezy infants.

Authors:  C O'Callaghan; A D Milner; A Swarbrick
Journal:  Lancet       Date:  1986 Dec 20-27       Impact factor: 79.321

6.  Epidemiology of adverse reactions in anaesthesia in the United Kingdom.

Authors:  R S Clarke
Journal:  Klin Wochenschr       Date:  1982-09-01

Review 7.  Pharmaceutical excipients. Adverse effects associated with inactive ingredients in drug products (Part I).

Authors:  L K Golightly; S S Smolinske; M L Bennett; E W Sutherland; B H Rumack
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Mar-Apr

8.  Tartrazine induced histamine release in vivo in normal subjects.

Authors:  R D Murdoch; I Pollock; S Naeem
Journal:  J R Coll Physicians Lond       Date:  1987-10
  8 in total

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