[The University Hospital of Children Queen Fabiola is twenty years old!].

HUDERF is the only pediatric hospital autonomous in Belgium because the other academic pediatric departments are included in general hospitals. However, the model of the children hospital is the most common, both in the industrial nations and in the undeveloped countries and evolves in hospital "mother-child" for the optimaisation of cares in infants that often begin from before the birth, for example in the case of predictable genetic diseases. The children's first hospitals date of more than 150 years ago as that of London for example. Huderf considerably developed in 20 years: it is the topic of this article. Its future is shared with the academic Hospital today and St-Pierre Hospital through the Iris-ULB convention.