| Literature DB >> 21818482 |
Toru Komatsu1, Daihi Oushiki, Aoi Takeda, Masaki Miyamura, Tasuku Ueno, Takuya Terai, Kenjiro Hanaoka, Yasuteru Urano, Tomoko Mineno, Tetsuo Nagano.
Abstract
We studied the photobleaching of a library of boron dipyrromethene (BODIPY) derivatives with a range of electron densities, and found that the photobleaching rate is influenced by the electron-withdrawing capacity of the substituents. Electron-deficient BODIPYs generated less singlet oxygen, were less reactive to singlet oxygen, and were highly resistant to photobleaching. We confirmed the utility of one of these fluorophores, 2,6-diCO(2)R-BDP, for visualizing EGF receptor dynamics in cells expressing an SNAP-tagged EGF receptor.Entities:
Mesh:
Substances:
Year: 2011 PMID: 21818482 DOI: 10.1039/c1cc13367e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222