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Literature DB >> 21817120

Successful treatment of brainstem blastomycosis with fluconazole.

Abstract

The lipid formulation of amphotericin B is the initial drug of choice for central nervous system blastomycosis, but it is costly and associated with significant toxicity. This case report details a patient with primary pulmonary blastomycosis with dissemination to the skin, one joint, and the brainstem that was successfully treated solely with high-dose fluconazole.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2011 PMID： 21817120 PMCID： PMC3355743 DOI： 10.3121/cmr.2011.1023

Source DB: PubMed Journal: Clin Med Res ISSN： 1539-4182

12 in total

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Journal: Infect Dis Clin North Am Date: 2003-03 Impact factor: 5.982

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5. Recurrent central nervous system blastomycosis in an immunocompetent child treated successfully with sequential liposomal amphotericin B and voriconazole.

Authors: Jyoti Panicker; Thomas Walsh; Naynesh Kamani
Journal: Pediatr Infect Dis J Date: 2006-04 Impact factor: 2.129

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Authors: P P Cook
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Authors: Carol A Kauffman
Journal: J Fungi (Basel) Date: 2019-07-18

2 in total

Successful treatment of brainstem blastomycosis with fluconazole.

Review 1. Blastomycosis.

2. Favourable outcome of blastomycosis of the brain stem with fluconazole and flucytosine treatment.

3. Treatment of blastomycosis with higher doses of fluconazole. The National Institute of Allergy and Infectious Diseases Mycoses Study Group.

Review 4. Fluconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial and systemic mycoses.

5. Recurrent central nervous system blastomycosis in an immunocompetent child treated successfully with sequential liposomal amphotericin B and voriconazole.

6. Amphotericin B lipid complex for the treatment of recurrent blastomycosis of the brain in a patient previously treated with itraconazole.

7. Successful treatment of cerebral blastomycosis with voriconazole.

Review 8. Amphotericin B: 30 years of clinical experience.

9. Blastomycosis of the central nervous system: a multicenter review of diagnosis and treatment in the modern era.

Review 10. Lipid formulations of amphotericin B: clinical efficacy and toxicities.

Review 1. CYP51 as drug targets for fungi and protozoan parasites: past, present and future.

Review 2. Central Nervous System Infection with Other Endemic Mycoses: Rare Manifestation of Blastomycosis, Paracoccidioidomycosis, Talaromycosis, and Sporotrichosis.