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Literature DB >> 21816914

Trastuzumab (herceptin).

Abstract

Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.

Entities: Chemical Disease Gene Species

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Year: 2011 PMID： 21816914 PMCID： PMC7964332 DOI： 10.3174/ajnr.A2619

Source DB: PubMed Journal: AJNR Am J Neuroradiol ISSN： 0195-6108 Impact factor: 3.825

5 in total

Review 1. Cetuximab: an epidermal growth factor receptor monoclonal antibody for the treatment of colorectal cancer.

Authors: Siu-Fun Wong
Journal: Clin Ther Date: 2005-06 Impact factor: 3.393

Review 2. Review of epidermal growth factor receptor biology.

Authors: Roy S Herbst
Journal: Int J Radiat Oncol Biol Phys Date: 2004 Impact factor: 7.038

3. Trends in breast cancer by race and ethnicity.

Authors: Asma Ghafoor; Ahmedin Jemal; Elizabeth Ward; Vilma Cokkinides; Robert Smith; Michael Thun
Journal: CA Cancer J Clin Date: 2003 Nov-Dec Impact factor: 508.702

Review 4. HER1/EGFR targeting: refining the strategy.

Authors: Román Pérez-Soler
Journal: Oncologist Date: 2004

Review 5. Biologic and therapeutic role of HER2 in cancer.

Authors: Sylvie Ménard; Serenella Marja Pupa; Manuela Campiglio; Elda Tagliabue
Journal: Oncogene Date: 2003-09-29 Impact factor: 9.867

5 in total

12 in total

Review 1. Attenuation of p53 mutant as an approach for treatment Her2-positive cancer.

Authors: Olga Fedorova; Alexandra Daks; Oleg Shuvalov; Alena Kizenko; Alexey Petukhov; Yulia Gnennaya; Nikolai Barlev
Journal: Cell Death Discov Date: 2020-10-10

2. Trastuzumab as a preoperative monotherapy does not inhibit HER2 downstream signaling in HER2-positive breast cancer.

Authors: Maëva Lion; Alexandre Harlé; Julia Salleron; Carole Ramacci; Mario Campone; Jean-Louis Merlin
Journal: Oncol Lett Date: 2016-07-20 Impact factor: 2.967

Review 3. Recent developments in receptor tyrosine kinases targeted anticancer therapy.

Authors: Samir H Raval; Ratn D Singh; Dilip V Joshi; Hitesh B Patel; Shailesh K Mody
Journal: Vet World Date: 2016-01-29

4. Anti-cancer effects of Bifidobacterium species in colon cancer cells and a mouse model of carcinogenesis.

Authors: Asadollahi Parisa; Ghanavati Roya; Rohani Mahdi; Razavi Shabnam; Esghaei Maryam; Talebi Malihe
Journal: PLoS One Date: 2020-05-13 Impact factor: 3.240

5. Doxorubicin conjugated with a trastuzumab epitope and an MMP-2 sensitive peptide linker for the treatment of HER2-positive breast cancer.

Authors: Yiwen You; Zhiyuan Xu; Yun Chen
Journal: Drug Deliv Date: 2018-11 Impact factor: 6.419

6. Durable clinical benefit to trastuzumab and chemotherapy in a patient with metastatic colon adenocarcinoma harboring ERBB2 amplification.

Authors: Umut Disel; Alexis Germain; Bahar Yilmazel; Huseyin Abali; Filiz Aka Bolat; Roman Yelensky; Julia A Elvin; Doron Lipson; Juliann Chmielecki; Kai Wang; Philip J Stephens; Jeffrey S Ross; Vincent A Miller; Siraj M Ali; Thomas J George
Journal: Oncoscience Date: 2015-07-01

7. STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits.

Authors: Seyung S Chung; Nolan Giehl; Yanyuan Wu; Jaydutt V Vadgama
Journal: Int J Oncol Date: 2013-11-29 Impact factor: 5.650

8. Evaluation of analytical similarity between trastuzumab biosimilar CT-P6 and reference product using statistical analyses.

Authors: Jihun Lee; Hyun Ah Kang; Jin Soo Bae; Kyu Dae Kim; Kyoung Hoon Lee; Ki Jung Lim; Min Joo Choo; Shin Jae Chang
Journal: MAbs Date: 2018-03-14 Impact factor: 5.857

Review 9. Current Strategies and Applications for Precision Drug Design.

Authors: Chen Wang; Pan Xu; Luyu Zhang; Jing Huang; Kongkai Zhu; Cheng Luo
Journal: Front Pharmacol Date: 2018-07-18 Impact factor: 5.810

10. African Vegetables (Clerodendrum volibile Leaf and Irvingia gabonensis Seed Extracts) Effectively Mitigate Trastuzumab-Induced Cardiotoxicity in Wistar Rats.

Authors: Olufunke Olorundare; Adejuwon Adeneye; Akinyele Akinsola; Sunday Soyemi; Alban Mgbehoma; Ikechukwu Okoye; James M Ntambi; Hasan Mukhtar
Journal: Oxid Med Cell Longev Date: 2020-10-15 Impact factor: 6.543