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Literature DB >> 21816341

CUL4B: trash talking at chromatin.

Abstract

In this issue, Nakagawa and Xiong (2011) reveal a mechanism targeting WDR5 for proteolysis dependent on the X-linked mental retardation gene, CUL4B. This provides a link between the stability of a chromatin factor and gene expression implicated in neurological pathogenesis.

Entities: Disease Gene Species

Year: 2011 PMID： 21816341 PMCID： PMC3151490 DOI： 10.1016/j.molcel.2011.07.015

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

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References

8 in total

Review 1. The genetic landscape of intellectual disability arising from chromosome X.

Authors: Jozef Gécz; Cheryl Shoubridge; Mark Corbett
Journal: Trends Genet Date: 2009-06-24 Impact factor: 11.639

2. PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.

Authors: Weijun Feng; Masato Yonezawa; Jing Ye; Thomas Jenuwein; Ingrid Grummt
Journal: Nat Struct Mol Biol Date: 2010-03-07 Impact factor: 15.369

3. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Authors: Shigeki Iwase; Fei Lan; Peter Bayliss; Luis de la Torre-Ubieta; Maite Huarte; Hank H Qi; Johnathan R Whetstine; Azad Bonni; Thomas M Roberts; Yang Shi
Journal: Cell Date: 2007-02-22 Impact factor: 41.582

4. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.

Authors: Daniela Kleine-Kohlbrecher; Jesper Christensen; Julien Vandamme; Iratxe Abarrategui; Mads Bak; Niels Tommerup; Xiaobing Shi; Or Gozani; Juri Rappsilber; Anna Elisabetta Salcini; Kristian Helin
Journal: Mol Cell Date: 2010-03-25 Impact factor: 17.970

5. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

Authors: Akihiko Yokoyama; Zhong Wang; Joanna Wysocka; Mrinmoy Sanyal; Deborah J Aufiero; Issay Kitabayashi; Winship Herr; Michael L Cleary
Journal: Mol Cell Biol Date: 2004-07 Impact factor: 4.272

CUL4B: trash talking at chromatin.

Review 1. The genetic landscape of intellectual disability arising from chromosome X.

2. PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.

3. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

4. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.

5. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

6. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

7. Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression.

8. Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy.