Literature DB >> 21814677

An efficient approach to pyrazolo[5,1-a]isoquinolin-2-amines via a silver(I)-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and nitrile.

Xingxin Yu1, Qin Yang, Honglei Lou, Yiyuan Peng, Jie Wu.   

Abstract

A three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and nitrile catalyzed by silver triflate under mild conditions is reported, which generates pyrazolo[5,1-a]isoquinolin-2-amines in good to excellent yields.

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Year:  2011        PMID： 21814677     DOI： 10.1039/c1ob05917c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Methyl (3S,10b'S)-5-chloro-9'-fluoro-1-methyl-2-oxo-5'-phenyl-10b'H-spiro-[indoline-3,1'-pyrazolo-[3,2-a]iso-quinoline]-2'-carboxyl-ate.

Authors:  Piskala Subburaman Kannan; Panneerselvam Yuvaraj; Boreddy Siva Rami Reddy; Rajamani Raja; Arunachalathevar Subbiahpandi
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-05-04

2.  Benzyl 5-phenyl-pyrazolo-[5,1-a]isoquino-line-1-carboxyl-ate.

Authors:  Yu-Kun Lu; Xiao Yao; Li-Wen Luo; Ren-Qing Lü; Yun-Qi Liu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-11-30

Review 3.  Silver and gold-catalyzed multicomponent reactions.

Authors:  Giorgio Abbiati; Elisabetta Rossi
Journal:  Beilstein J Org Chem       Date:  2014-02-26       Impact factor: 2.883

4.  'One-pot' synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a silver(I)-catalyzed cascade approach.

Authors:  Baifeng Jiang; Yu Zhou; Qingya Kong; Hualiang Jiang; Hong Liu; Jian Li
Journal:  Molecules       Date:  2013-01-11       Impact factor: 4.411
  4 in total

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