Literature DB >> 21813557

Stem cells in bone diseases: current clinical practice.

Shaul Beyth1, Josh Schroeder, Meir Liebergall.   

Abstract

INTRODUCTION: Bone is an obvious candidate tissue for stem cell therapy. This review provides an update of existing stem cell-based clinical treatments for bone pathologies. SOURCES OF DATA: A systematic computerized literature search was conducted. The following databases were accessed on 10 February 2011: NIH clinical trials database, PubMed, Ovid and Cochrane Reviews. AREAS OF AGREEMENT: Stem cell therapy offers new options for bone conditions, both acquired and inherited. AREAS OF CONTROVERSY: There is still no agreement on the exact definition of 'mesenchymal stem cells'. Consequently, it is difficult to appreciate the effect of culture expansion and the feasibility of allogeneic transplantation. GROWING POINTS: Based on the sound foundations of pre-clinical research, stem cell-based treatments and protocols have recently emerged. AREAS TIMELY FOR DEVELOPING RESEARCH: Well-designed prospective clinical trials are needed in order to establish and develop stem cell therapy for bone diseases.

Entities:  

Mesh：

Year:  2011        PMID： 21813557     DOI： 10.1093/bmb/ldr035

Source DB:  PubMed          Journal:  Br Med Bull        ISSN： 0007-1420            Impact factor:   4.291


  13 in total

Review 1.  Concise review: the clinical application of mesenchymal stem cells for musculoskeletal regeneration: current status and perspectives.

Authors:  Andre F Steinert; Lars Rackwitz; Fabian Gilbert; Ulrich Nöth; Rocky S Tuan
Journal:  Stem Cells Transl Med       Date:  2012-02-22       Impact factor: 6.940

2.  Interferon gamma and T cells inhibit osteogenesis induced by allogeneic mesenchymal stromal cells.

Authors:  Abhijit S Dighe; Scott Yang; Vedavathi Madhu; Gary Balian; Quanjun Cui
Journal:  J Orthop Res       Date:  2012-08-10       Impact factor: 3.494

3.  MESENCHYMAL STROMAL CELLS AND THEIR ORTHOPAEDIC APPLICATIONS.

Authors:  Lindsay A Bashur; Guang Zhou
Journal:  Case Orthop J       Date:  2012

4.  Identification of the Human Skeletal Stem Cell.

Authors:  Charles K F Chan; Gunsagar S Gulati; Rahul Sinha; Justin Vincent Tompkins; Michael Lopez; Ava C Carter; Ryan C Ransom; Andreas Reinisch; Taylor Wearda; Matthew Murphy; Rachel E Brewer; Lauren S Koepke; Owen Marecic; Anoop Manjunath; Eun Young Seo; Tripp Leavitt; Wan-Jin Lu; Allison Nguyen; Stephanie D Conley; Ankit Salhotra; Thomas H Ambrosi; Mimi R Borrelli; Taylor Siebel; Karen Chan; Katharina Schallmoser; Jun Seita; Debashis Sahoo; Henry Goodnough; Julius Bishop; Michael Gardner; Ravindra Majeti; Derrick C Wan; Stuart Goodman; Irving L Weissman; Howard Y Chang; Michael T Longaker
Journal:  Cell       Date:  2018-09-20       Impact factor: 41.582

5.  Biphasic Calcium Phosphate Biomaterials: Stem Cell-Derived Osteoinduction or In Vivo Osteoconduction? Novel Insights in Maxillary Sinus Augmentation by Advanced Imaging.

Authors:  Giovanna Iezzi; Antonio Scarano; Luca Valbonetti; Serena Mazzoni; Michele Furlani; Carlo Mangano; Aurelio Muttini; Mario Raspanti; Barbara Barboni; Adriano Piattelli; Alessandra Giuliani
Journal:  Materials (Basel)       Date:  2021-04-23       Impact factor: 3.623

6.  Lentivirus transduced interleukin-1 receptor antagonist gene expression in murine bone marrow-derived mesenchymal stem cells in vitro.

Authors:  Tao He; Guanghao Chi; Bo Tian; Tingting Tang; Kerong Dai
Journal:  Mol Med Rep       Date:  2015-06-26       Impact factor: 2.952

Review 7.  Interactions between MSCs and immune cells: implications for bone healing.

Authors:  Tracy K Kovach; Abhijit S Dighe; Peter I Lobo; Quanjun Cui
Journal:  J Immunol Res       Date:  2015-04-27       Impact factor: 4.818

8.  Synthetic bone substitute engineered with amniotic epithelial cells enhances bone regeneration after maxillary sinus augmentation.

Authors:  Barbara Barboni; Carlo Mangano; Luca Valbonetti; Giuseppe Marruchella; Paolo Berardinelli; Alessandra Martelli; Aurelio Muttini; Annunziata Mauro; Rossella Bedini; Maura Turriani; Raffaella Pecci; Delia Nardinocchi; Vincenzo Luca Zizzari; Stefano Tetè; Adriano Piattelli; Mauro Mattioli
Journal:  PLoS One       Date:  2013-05-17       Impact factor: 3.240

9.  New insights into osteogenic and chondrogenic differentiation of human bone marrow mesenchymal stem cells and their potential clinical applications for bone regeneration in pediatric orthopaedics.

Authors:  Nicola Giuliani; Gina Lisignoli; Marina Magnani; Costantina Racano; Marina Bolzoni; Benedetta Dalla Palma; Angelica Spolzino; Cristina Manferdini; Caterina Abati; Denise Toscani; Andrea Facchini; Franco Aversa
Journal:  Stem Cells Int       Date:  2013-05-23       Impact factor: 5.443

10.  Bone progenitors produced by direct osteogenic differentiation of the unprocessed bone marrow demonstrate high osteogenic potential in vitro and in vivo.

Authors:  Irene Ginis; Miron Weinreb; Natalie Abramov; Doron Shinar; Shoshana Merchav; Aharon Schwartz; Mitchell Shirvan
Journal:  Biores Open Access       Date:  2012-04
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