| Literature DB >> 21813545 |
Kuniyuki Oka1, Reizo Nagayama, Nobuo Yonekawa, Takeshi Nihei, Norimasa Sando, Yasushi Yatabe, Naoyoshi Mori.
Abstract
This report describes a 60-year-old man with concurrent gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) and classical Hodgkin lymphoma (CHL). Atypical, medium-sized, lymphoid cells proliferated in the mucosa to muscular layer of the stomach showing a lymphoepithelial lesion; admixed with Hodgkin/Reed-Sternberg (HRS) cells and an inflammatory cell background. MALT lymphoma cells expressed CD20, CD79a, PAX5, and BOB.1, and HRS cells expressed CD30, CD15, Epstein-Barr virus-encoded RNA, and EBV-latent membrane protein 1. Only CHL invaded into the regional lymph nodes. Two possibilities of transformation of MALT lymphoma into CHL and de novo CHL within MALT lymphoma are discussed.Entities:
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Year: 2011 PMID: 21813545 DOI: 10.1177/1066896911417242
Source DB: PubMed Journal: Int J Surg Pathol ISSN: 1066-8969 Impact factor: 1.271