Literature DB >> 21812579

A mathematical model for the dynamics of HIV/AIDS with gradual behaviour change.

F Baryarama1, J Y T Mugisha, L S Luboobi.   

Abstract

An HIV/AIDS model that incorporates gradual behaviour change is formulated with a variable force of infection for the adult population. The variability is modelled using a general function of time since introduction of the initial infective and exemplified for three specific functions. Expressions for the time taken for the reproductive number to reduce to unity and expressions for the time taken to attain a stationary steady state are deduced and discussed. Model projections for urban, peri-urban and rural Uganda are compared with corresponding antenatal clinic sites prevalence trends. The analysis shows that the dramatic decline in HIV prevalence in Uganda in the early 1990s was only possible through drastic declines in the force of infection. Since prevalence was high and reductions in frequency of sexual acts was minimal, the huge reduction could be attributed to reductions in probability of transmission per sexual act probably due to increased selective condom use among high risk sexual partnerships since overall condom use was low.

Entities:  

Year:  2006        PMID: 21812579     DOI: 10.1080/10273660600906960

Source DB:  PubMed          Journal:  Comput Math Methods Med        ISSN: 1748-670X            Impact factor:   2.238


  2 in total

1.  A note on the impact of late diagnosis on HIV/AIDS dynamics: a mathematical modelling approach.

Authors:  J Mushanyu
Journal:  BMC Res Notes       Date:  2020-07-16

2.  Effects of density of infected population to the spreading of HIV epidemic in communities.

Authors:  Simon Mukwembi
Journal:  Physica A       Date:  2011-06-23       Impact factor: 3.263

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.