Literature DB >> 21809913

When will thyrotropin receptor antagonists and inverse thyrotropin receptor agonists become available for clinical use?

Charles H Emerson.   

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Year:  2011        PMID： 21809913     DOI： 10.1089/thy.2011.2108.ed

Source DB:  PubMed          Journal:  Thyroid        ISSN： 1050-7256            Impact factor:   6.568


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  4 in total

1.  A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts.

Authors:  Susanne Neumann; Arthur Pope; Elizabeth Geras-Raaka; Bruce M Raaka; Rebecca S Bahn; Marvin C Gershengorn
Journal:  Thyroid       Date:  2012-07-11       Impact factor: 6.568

2.  A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice.

Authors:  Susanne Neumann; Eshel A Nir; Elena Eliseeva; Wenwei Huang; Juan Marugan; Jingbo Xiao; Andrés E Dulcey; Marvin C Gershengorn
Journal:  Endocrinology       Date:  2013-12-04       Impact factor: 4.736

3.  Synthetic gene network restoring endogenous pituitary-thyroid feedback control in experimental Graves' disease.

Authors:  Pratik Saxena; Ghislaine Charpin-El Hamri; Marc Folcher; Henryk Zulewski; Martin Fussenegger
Journal:  Proc Natl Acad Sci U S A       Date:  2016-01-19       Impact factor: 11.205

4.  Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70TM a human monoclonal autoantibody to the TSH receptor with TSH antagonist activity.

Authors:  Jadwiga Furmaniak; Jane Sanders; Jill Clark; Jane Wilmot; Paul Sanders; Yang Li; Bernard Rees Smith
Journal:  Auto Immun Highlights       Date:  2019-11-07
  4 in total

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