Literature DB >> 21808242

esBAF safeguards Stat3 binding to maintain pluripotency.

Noa Novershtern, Jacob H Hanna.   

Abstract

How the unique chromatin configuration of embryonic stem cells (ESCs) integrates inputs from exogenous stimuli to maintain pluripotency remains largely unknown. The ESC-specific ATP-dependent chromatin-remodelling (esBAF) complex maintains the accessibility of the target sites of Stat3, a leukaemia inhibitory factor (LIF) signalling effector, by preventing repressive localized polycomb-mediated trimethylation of Lys 27 of histone 3 (H3K27me3).

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Year:  2011        PMID： 21808242     DOI： 10.1038/ncb2311

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

Review 1.  Nuclear reprogramming to a pluripotent state by three approaches.

Authors:  Shinya Yamanaka; Helen M Blau
Journal:  Nature       Date:  2010-06-10       Impact factor: 49.962

Review 2.  Polycomb group proteins set the stage for early lineage commitment.

Authors:  Lauren E Surface; Seraphim R Thornton; Laurie A Boyer
Journal:  Cell Stem Cell       Date:  2010-09-03       Impact factor: 24.633

3.  Female human iPSCs retain an inactive X chromosome.

Authors:  Jason Tchieu; Edward Kuoy; Mark H Chin; Hung Trinh; Michaela Patterson; Sean P Sherman; Otaren Aimiuwu; Anne Lindgren; Shahrad Hakimian; Jerome A Zack; Amander T Clark; April D Pyle; William E Lowry; Kathrin Plath
Journal:  Cell Stem Cell       Date:  2010-08-19       Impact factor: 24.633

Review 4.  Chromatin in pluripotent embryonic stem cells and differentiation.

Authors:  Eran Meshorer; Tom Misteli
Journal:  Nat Rev Mol Cell Biol       Date:  2006-05-17       Impact factor: 94.444

5.  An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network.

Authors:  Lena Ho; Raja Jothi; Jehnna L Ronan; Kairong Cui; Keji Zhao; Gerald R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-11       Impact factor: 11.205

6.  An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

Authors:  Lena Ho; Jehnna L Ronan; Jiang Wu; Brett T Staahl; Lei Chen; Ann Kuo; Julie Lessard; Alexey I Nesvizhskii; Jeff Ranish; Gerald R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-11       Impact factor: 11.205

7.  Epigenomics: a roadmap, but to where?

Authors:  Hiten D Madhani; Nicole J Francis; Robert E Kingston; Roger D Kornberg; Danesh Moazed; Geeta J Narlikar; Barbara Panning; Kevin Struhl
Journal:  Science       Date:  2008-10-03       Impact factor: 47.728

8.  An extended transcriptional network for pluripotency of embryonic stem cells.

Authors:  Jonghwan Kim; Jianlin Chu; Xiaohua Shen; Jianlong Wang; Stuart H Orkin
Journal:  Cell       Date:  2008-03-21       Impact factor: 41.582

9.  Stat3 activation is limiting for reprogramming to ground state pluripotency.

Authors:  Jian Yang; Anouk L van Oosten; Thorold W Theunissen; Ge Guo; Jose C R Silva; Austin Smith
Journal:  Cell Stem Cell       Date:  2010-09-03       Impact factor: 24.633

10.  esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function.

Authors:  Lena Ho; Erik L Miller; Jehnna L Ronan; Wen Qi Ho; Raja Jothi; Gerald R Crabtree
Journal:  Nat Cell Biol       Date:  2011-07-24       Impact factor: 28.824
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  2 in total

1.  Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome.

Authors:  Sarah J Hainer; Thomas G Fazzio
Journal:  Cell Rep       Date:  2015-09-24       Impact factor: 9.423

2.  Regulation of germ layer formation by pluripotency factors during embryogenesis.

Authors:  Ying Cao
Journal:  Cell Biosci       Date:  2013-03-11       Impact factor: 7.133
  2 in total

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