Literature DB >> 21806530

Relationship of urinary sodium and sodium-to-potassium ratio to blood pressure in older adults in Australia.

Catherine E Huggins1, Sharleen O'Reilly, Maree Brinkman, Allison Hodge, Graham G Giles, Dallas R English, Caryl A Nowson.   

Abstract

OBJECTIVE: To assess the relationship between dietary sodium intake, as measured by urinary electrolyte excretion, and blood pressure within a population of older Australian adults. DESIGN, SETTING AND PARTICIPANTS: A cross-sectional study of adults enrolled in the Melbourne Collaborative Cohort Study, stratified by sex, country of birth (Italy, Greece, Australia/New Zealand) and age (50-59 and 60-75 years). Blood pressure measurements were taken in 2003-2007 and 24-hour urine collections in 2007-2008. MAIN OUTCOME MEASURES: 24-hour urinary excretion of sodium and potassium, urinary sodium-to-potassium ratio, and clinic blood pressure measurement.
RESULTS: The mean ± SD age of 783 participants was 64.0 ± 6.3 years. Mean ± SD urinary sodium was 155.1 ± 63.1 mmol/day (8.9 ± 3.6 g salt/day), urinary potassium was 82.3 ± 27.9 mmol/day, and urinary sodium-to-potassium ratio was 1.99 ± 0.83. In the 587 participants with blood pressure measurements, urinary sodium and the sodium-to-potassium ratio were both associated with systolic blood pressure in all adjusted and unadjusted models (mmHg change per 100 mmol/day increase in sodium: regression coefficient, 2.3, 95% CI, 0.1-4.6; P = 0.049, adjusted for age, sex, body mass index, country of birth and antihypertensive medication use).
CONCLUSION: This study has demonstrated, for the first time within an Australian population sample of older adults, that sodium intake is positively associated with blood pressure. These results suggest that a population-wide reduction in sodium intake could be effective in reducing blood pressure in adults in Australia.

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Year:  2011        PMID: 21806530     DOI: 10.5694/j.1326-5377.2011.tb03239.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  27 in total

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