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Literature DB >> 21806384

Neurobiological correlates of cognitions in fear and anxiety: a cognitive-neurobiological information-processing model.

Stefan G Hofmann¹, Kristen K Ellard, Greg J Siegle.

Abstract

We review likely neurobiological substrates of cognitions related to fear and anxiety. Cognitive processes are linked to abnormal early activity reflecting hypervigilance in subcortical networks involving the amygdala, hippocampus, and insular cortex, and later recruitment of cortical regulatory resources, including activation of the anterior cingulate cortex and prefrontal cortex to implement avoidant response strategies. Based on this evidence, we present a cognitive-neurobiological information-processing model of fear and anxiety, linking distinct brain structures to specific stages of information processing of perceived threat.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21806384 PMCID： PMC3229257 DOI： 10.1080/02699931.2011.579414

Source DB: PubMed Journal: Cogn Emot ISSN： 0269-9931

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