| Literature DB >> 21806011 |
Wendy L Popplewell1, Ranjala Ratnayake, Jennifer A Wilson, John A Beutler, Nancy H Colburn, Curtis J Henrich, James B McMahon, Tawnya C McKee.
Abstract
Grassypeptolides F (1) and G (2), bis-thiazoline-containing cyclic depsipeptides with a rare β-amino acid, extensive N-methylation, and a large number of d-amino acids, are reported from an extract of the Palauan cyanobacterium Lyngbya majuscula. Both 1 and 2 were found to have moderate inhibitory activity against the transcription factor AP-1 (IC₅₀ = 5.2 and 6.0 μM, respectively).Entities:
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Year: 2011 PMID： 21806011 PMCID： PMC3162996 DOI： 10.1021/np2005083
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050