Literature DB >> 21805970

Copper-catalyzed synthesis of quinoxalines with o-phenylenediamine and terminal alkyne in the presence of bases.

Wen Wang1, Yongwen Shen, Xu Meng, Mingming Zhao, Yongxin Chen, Baohua Chen.   

Abstract

A novel way of synthesizing quinoxalines efficiently through cyclization of o-phenylenediamine and terminal alkyne by Cu(II) and bases is developed. This reaction proceeds smoothly to give the products in moderate to good yields.

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Year:  2011        PMID: 21805970     DOI: 10.1021/ol201664x

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Nucleophilic Substitution on 2-Monosubstituted Quinoxalines Giving 2,3-Disubstituted Quinoxalines: Investigating the Effect of the 2-Substituent.

Authors:  Ndumiso Thamsanqa Ndlovu; Winston Nxumalo
Journal:  Molecules       Date:  2016-09-30       Impact factor: 4.411

2.  PIDA-mediated intramolecular oxidative C-N bond formation for the direct synthesis of quinoxalines from enaminones.

Authors:  Hong Zhang; Jinhai Shen; Zhenhui Yang; Xiuling Cui
Journal:  RSC Adv       Date:  2019-03-07       Impact factor: 4.036

  2 in total

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