Literature DB >> 21805601

Incidence, timing, and predictors of valve dislodgment during TAVI with the Medtronic Corevalve System.

Nicolas M Van Mieghem1, Carl J Schultz, Robert M A van der Boon, Rutger-Jan Nuis, Apostolos Tzikas, Marcel L Geleijnse, Ron T van Domburg, Patrick W Serruys, Peter P T de Jaegere.   

Abstract

OBJECTIVES: To determine the incidence, timing and predictors of periprocedural valve dislodgment with the Medtronic Corevalve System (MCS).
BACKGROUND: Periprocedural valve dislodgment may occur during transcatheter aortic valve implantation (TAVI).
METHODS: Ninety-eight consecutive patients underwent TAVI with the MCS after a comprehensive baseline assessment including invasive angiography, echocardiography, and Multi-Slice Computed Tomography (MSCT). The invasive monitoring charts and angiographic studies of all TAVI procedures were reviewed to determine the incidence and timing of valve dislodgment.
RESULTS: Valve dislodgment occurred in 18 patients. Patients with valve dislodgment had a larger Aortic Valve Area (0.76 ± 0.25 cm(2) vs. 0.61 ± 0.19 cm(2) , P = 0.007), lower mean transaortic gradient (37.65 ± 14.62 mm Hg vs. 47.11 ± 16.08 mm Hg, P = 0.03) and significantly less aortic root calcification (Agatston score median 1951 AU (IQR, 799-3103) vs. 3289 AU (IQR 2097-4481), P = 0.016). A lower aortic root calcium score (Agatston score < 2359 AU) was the single independent predictor for valve dislodgment (OR 3.10, 1.09-8.84). After valve dislodgment, the valve could be successfully retrieved and implanted in the proper anatomic location in all cases. Valve dislodgment was associated with a lower incidence of post-procedural AR ≥ 2 (11.1% vs. 34.6%, P = 0.05). There were no relevant procedural or clinical implications to valve dislodgment.
CONCLUSIONS: The incidence of periprocedural valve dislodgment was 18% in these series. Less aortic root calcification appeared the single independent predictor.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 21805601     DOI: 10.1002/ccd.23275

Source DB:  PubMed          Journal:  Catheter Cardiovasc Interv        ISSN: 1522-1946            Impact factor:   2.692


  7 in total

1.  Aortic valve calcium load before TAVI: Is it important?

Authors:  Martin Haensig; Ardawan Julian Rastan
Journal:  Ann Cardiothorac Surg       Date:  2012-07

2.  Valve-in-valve-in-valve transcatheter aortic valve implantation to treat a degenerated surgical bioprosthesis in a subaortic position.

Authors:  Rutger-Jan Nuis; Luis M Benitez; Carlos A Nader; Sergio Perez; Eduardo J de Marchena; Antonio E Dager
Journal:  Tex Heart Inst J       Date:  2013

3.  Imaging in Transcatheter Aortic Valve Replacement (TAVR): role of the radiologist.

Authors:  Diana E Litmanovich; Eduard Ghersin; David A Burke; Jeffrey Popma; Maryam Shahrzad; Alexander A Bankier
Journal:  Insights Imaging       Date:  2014-01-21

4.  Recovery from anemia in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation--prevalence, predictors and clinical outcome.

Authors:  Ole De Backer; Samer Arnous; Jacob Lønborg; Matthew Brooks; Luigi Biasco; Anders Jönsson; Olaf W Franzen; Lars Søndergaard
Journal:  PLoS One       Date:  2014-12-01       Impact factor: 3.240

Review 5.  Transcatheter aortic valve implantation.

Authors:  Thomas M Snow; Neil Moat; Sarah Barker; Alison Duncan; Carlo Di Mario
Journal:  Glob Cardiol Sci Pract       Date:  2012-08-30

6.  Complementary Role of the Computed Biomodelling through Finite Element Analysis and Computed Tomography for Diagnosis of Transcatheter Heart Valve Thrombosis.

Authors:  Francesco Nappi; Laura Mazzocchi; Sanjeet Singh Avtaar Singh; Simone Morganti; Jean-Louis Sablayrolles; Christophe Acar; Ferdinando Auricchio
Journal:  Biomed Res Int       Date:  2018-10-22       Impact factor: 3.411

Review 7.  Cardiac Computed Tomography: Application in Valvular Heart Disease.

Authors:  Kush P Patel; Sebastian Vandermolen; Anna S Herrey; Emma Cheasty; Leon Menezes; James C Moon; Francesca Pugliese; Thomas A Treibel
Journal:  Front Cardiovasc Med       Date:  2022-03-24
  7 in total

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