Literature DB >> 21805092

Primary hypothyroidism presenting as pseudoacromegaly.

K V S Hari Kumar1, Altamash Shaikh, Irfan Anwar, P Prusty.   

Abstract

Pseudoacromegaly is a condition characterized by cutaneous manifestations of growth hormone excess but with normal growth hormone levels. This is described in patients with severe insulin resistance, pachydermoperiostitis, burnt out acromegaly and with intake of drugs like Minoxidil. Severe thyroid hormone deficiency rarely present with similar picture and the issue is further complicated in presence of pituitary hyperplasia. We report an unusual presentation of primary hypothyroidism with pseudoacromegaly and thyrotroph hyperplasia mimicking a pituitary macroadenoma. The thyrotroph hyperplasia resolved completely with levothyroxine therapy.

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Year:  2012        PMID: 21805092     DOI: 10.1007/s11102-011-0336-x

Source DB:  PubMed          Journal:  Pituitary        ISSN: 1386-341X            Impact factor:   4.107


  9 in total

1.  Large pituitary hyperplasia in severe primary hypothyroidism.

Authors:  E Passeri; A Tufano; M Locatelli; A G Lania; B Ambrosi; S Corbetta
Journal:  J Clin Endocrinol Metab       Date:  2011-01       Impact factor: 5.958

2.  EMO syndrome.

Authors:  K V S Hari Kumar; Y S Bisht; P Prusty
Journal:  J Postgrad Med       Date:  2011 Apr-Jun       Impact factor: 1.476

3.  A case of fugitive acromegaly, initially presented as invasive prolactinoma.

Authors:  Jung Soo Lim; Cheol Ryong Ku; Mi-Kyung Lee; Tai Seung Kim; Sun Ho Kim; Eun Jig Lee
Journal:  Endocrine       Date:  2010-04-24       Impact factor: 3.633

Review 4.  Cutaneous manifestations of thyroid disease.

Authors:  W R Heymann
Journal:  J Am Acad Dermatol       Date:  1992-06       Impact factor: 11.527

5.  Pseudoacromegaly induced by the long-term use of minoxidil.

Authors:  Kari H Nguyen; James G Marks
Journal:  J Am Acad Dermatol       Date:  2003-06       Impact factor: 11.527

6.  Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance.

Authors:  J S Flier; D E Moller; A C Moses; S O'Rahilly; R L Chaiken; F Grigorescu; D Elahi; B B Kahn; J E Weinreb; R Eastman
Journal:  J Clin Endocrinol Metab       Date:  1993-06       Impact factor: 5.958

7.  Congenital hypothyroidism simulating acromegaly - a diagnostic pitfall.

Authors:  Marek Ruchala; Ewelina Szczepanek; Monika Tamborska-Zedlewska; Agata Czarnywojtek; Ryszard Wasko; Jerzy Sowinski
Journal:  Neuro Endocrinol Lett       Date:  2009       Impact factor: 0.765

8.  Macroglossia in acromegaly and hypothyroidism.

Authors:  A L Wittmann
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1977-04-29

9.  A unique growth factor in patients with acromegaloidism.

Authors:  M W Ashcraft; P I Hartzband; A J Van Herle; N Bersch; D W Golde
Journal:  J Clin Endocrinol Metab       Date:  1983-08       Impact factor: 5.958

  9 in total
  1 in total

1.  Acromegaloid facial appearance: case report and literature review.

Authors:  Adline Ghazi; Shikha Khosla; Kenneth Becker
Journal:  Case Rep Endocrinol       Date:  2013-02-28
  1 in total

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