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Literature DB >> 21804616

Designing an organellar postal service: delivery of macromolecules to mitochondria in intact cells.

Francesco Bruni¹, Robert N Lightowlers.

Abstract

Mesh：

Substances：
Lipids

Year: 2011 PMID： 21804616 PMCID： PMC3149165 DOI： 10.1038/mt.2011.139

Source DB: PubMed Journal: Mol Ther ISSN： 1525-0016 Impact factor: 11.454

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References

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11 in total

Review 1. Development of mitochondrial gene replacement therapy.

Authors: Shaharyar M Khan; James P Bennett
Journal: J Bioenerg Biomembr Date: 2004-08 Impact factor: 2.945

2. Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.

Authors: Yukari Yasuzaki; Yuma Yamada; Hideyoshi Harashima
Journal: Biochem Biophys Res Commun Date: 2010-05-16 Impact factor: 3.575

3. MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion.

Authors: Yuma Yamada; Hidetaka Akita; Hiroyuki Kamiya; Kentaro Kogure; Takenori Yamamoto; Yasuo Shinohara; Kikuji Yamashita; Hideo Kobayashi; Hiroshi Kikuchi; Hideyoshi Harashima
Journal: Biochim Biophys Acta Date: 2007-11-12

4. Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Authors: Paula M Keeney; Caitlin K Quigley; Lisa D Dunham; Christina M Papageorge; Shilpa Iyer; Ravindar R Thomas; Kathleen M Schwarz; Patricia A Trimmer; Shaharyar M Khan; Francisco R Portell; Kristen E Bergquist; James P Bennett
Journal: Hum Gene Ther Date: 2009-08 Impact factor: 5.695

Designing an organellar postal service: delivery of macromolecules to mitochondria in intact cells.

Review 1. Development of mitochondrial gene replacement therapy.

2. Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes.

3. MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion.

4. Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Review 5. Targeting lipophilic cations to mitochondria.

6. Mitochondrial transformation: time for concerted action.

7. DNA-protein conjugates can enter mitochondria via the protein import pathway.

8. Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases.

9. Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid.

10. Protective effects of mitochondria-targeted antioxidant SkQ in aqueous and lipid membrane environments.