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Literature DB >> 21804580

The impact of mergers on pharmaceutical R&D.

Abstract

Mergers and acquisitions in the pharmaceutical industry have substantially reduced the number of major companies over the past 15 years. The short-term business rationale for this extensive consolidation might have been reasonable, but at what cost to research and development productivity?

Entities: Chemical

Mesh：

Year: 2011 PMID： 21804580 DOI： 10.1038/nrd3514

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

3 in total

Review 1. How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors: Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal: Nat Rev Drug Discov Date: 2010-02-19 Impact factor: 84.694

2. Rebuilding the R&D engine in big pharma.

Authors: Jean-Pierre Garnier
Journal: Harv Bus Rev Date: 2008-05

Review 3. Lessons from 60 years of pharmaceutical innovation.

Authors: Bernard Munos
Journal: Nat Rev Drug Discov Date: 2009-12 Impact factor: 84.694

3 in total

9 in total

1. Lessons from 54 years of pharmaceutical research.

Authors: Raymond A Firestone
Journal: Nat Rev Drug Discov Date: 2011-10-31 Impact factor: 84.694

2. A decade of change.

Authors: John Arrowsmith
Journal: Nat Rev Drug Discov Date: 2012-01-03 Impact factor: 84.694

3. Association Between the Number of Suppliers for Critical Antineoplastics and Drug Shortages: Implications for Future Drug Shortages and Treatment.

Authors: Helen M Parsons; Susanne Schmidt; Anand B Karnad; Yuanyuan Liang; Mary Jo Pugh; Erin R Fox
Journal: J Oncol Pract Date: 2016-02-02 Impact factor: 3.840

Review 4. The Valley of Death in anticancer drug development: a reassessment.

Authors: David J Adams
Journal: Trends Pharmacol Sci Date: 2012-03-10 Impact factor: 14.819

5. Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files.

Authors: Andrew S Bell; Joseph Bradley; Jeremy R Everett; Jens Loesel; David McLoughlin; James Mills; Marie-Claire Peakman; Robert E Sharp; Christine Williams; Hongyao Zhu
Journal: Mol Divers Date: 2016-09-08 Impact factor: 2.943

The impact of mergers on pharmaceutical R&D.

Review 1. How to improve R&D productivity: the pharmaceutical industry's grand challenge.

2. Rebuilding the R&D engine in big pharma.

Review 3. Lessons from 60 years of pharmaceutical innovation.

1. Lessons from 54 years of pharmaceutical research.

2. A decade of change.

3. Association Between the Number of Suppliers for Critical Antineoplastics and Drug Shortages: Implications for Future Drug Shortages and Treatment.

Review 4. The Valley of Death in anticancer drug development: a reassessment.

5. Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files.

Review 6. Reflections on the Future of Pharmaceutical Public-Private Partnerships: From Input to Impact.

Review 7. Changing R&D models in research-based pharmaceutical companies.

Review 8. Bridging academic science and clinical research in the search for novel targeted anti-cancer agents.

9. Roles of contract research organizations in translational medicine.