Literature DB >> 2180331

Norfloxacin for the prophylaxis of travelers' diarrhea in U.S. military personnel.

D A Scott1, R L Haberberger, S A Thornton, K C Hyams.   

Abstract

Norfloxacin, an oral fluoroquinolone (dose 400 mg daily), was compared to a placebo in a double blinded randomized trial for the prophylaxis of travelers' diarrhea. The study was of U.S. Navy and Marine Corps personnel on shore leave in Alexandria, Egypt. A total of 222 subjects were available (105 norfloxacin, 117 placebo). In the placebo group, 26% (30/117) developed acute diarrhea vs. 2% (2/105) in the norfloxacin group. There were no significant side effects in either group.

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Year:  1990        PMID: 2180331     DOI: 10.4269/ajtmh.1990.42.160

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  17 in total

Review 1.  Treatment of traveller's diarrhoea. Economic aspects.

Authors:  M A Thomson; I W Booth
Journal:  Pharmacoeconomics       Date:  1996-05       Impact factor: 4.981

2.  Travellers' diarrhoea: slow but steady progress.

Authors:  G C Cook
Journal:  Postgrad Med J       Date:  1993-07       Impact factor: 2.401

3.  Travelers' diarrhea: modern concepts and new developments.

Authors:  Andrew W DuPont; Herbert L DuPont
Journal:  Curr Treat Options Gastroenterol       Date:  2006-02

Review 4.  Quinolones in the treatment of acute bacterial diarrhoeal diseases.

Authors:  H E Akalin
Journal:  Drugs       Date:  1993       Impact factor: 9.546

5.  Travellers' diarrhea in children.

Authors:  Pierre J Plourde
Journal:  Paediatr Child Health       Date:  2003-02       Impact factor: 2.253

6.  Diarrhea in U.S. troops deployed to Thailand.

Authors:  P Echeverria; L R Jackson; C W Hoge; M K Arness; G R Dunnavant; R R Larsen
Journal:  J Clin Microbiol       Date:  1993-12       Impact factor: 5.948

Review 7.  Travellers' diarrhoea: contemporary approaches to therapy and prevention.

Authors:  Herbert L DuPont
Journal:  Drugs       Date:  2006       Impact factor: 9.546

Review 8.  The quinolones. An overview of their pharmacology.

Authors:  A Fitton
Journal:  Clin Pharmacokinet       Date:  1992       Impact factor: 6.447

Review 9.  Guidelines for the prevention and treatment of travelers' diarrhea: a graded expert panel report.

Authors:  Mark S Riddle; Bradley A Connor; Nicholas J Beeching; Herbert L DuPont; Davidson H Hamer; Phyllis Kozarsky; Michael Libman; Robert Steffen; David Taylor; David R Tribble; Jordi Vila; Philipp Zanger; Charles D Ericsson
Journal:  J Travel Med       Date:  2017-04-01       Impact factor: 8.490

10.  Summary of the Committee to Advise on Tropical Medicine and Travel (CATMAT) Statement on Travellers' Diarrhea.

Authors:  M Libman
Journal:  Can Commun Dis Rep       Date:  2015-11-05
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