Literature DB >> 21802227

Coronary thrombus and peracute myocardial infarction visualized by unenhanced postmortem MRI prior to autopsy.

Christian Jackowski1, Karin Hofmann, Nicole Schwendener, Wolf Schweitzer, Morten Keller-Sutter.   

Abstract

Sudden cardiac deaths are common within the community. They also constitute a substantial part of daily pathologic and forensic case work. However, macroscopic myocardial findings indicating acute ischemia are often absent. Then, diagnosis is based on coronary status in combination with indirect signs of acute cardiac failure. We present a case of sudden cardiac death where diagnosis was based on cardiac postmortem magnetic resonance imaging (pmMRI) findings already prior to autopsy: the heart's anterior basal ventricular septum showed hypointensities in T2-weighted images that raised suspicion of peracute ischemia. The lumen of the left anterior descending artery (LAD) exhibited a lack of otherwise discernible postmortem sedimentation of cellular blood components. Instead of a sharp border between serum and erythrocytes a homogeneous signal was seen within the narrowed lumen of the beginning LAD over a length of 1cm. Based on this, a thrombotic occlusion was assumed. Subsequent autopsy confirmed peracute septal myocardial ischemia secondary to a thrombotic occlusion of the LAD as concluded from the pmMRI.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID: 21802227     DOI: 10.1016/j.forsciint.2011.07.010

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  14 in total

Review 1.  Essentials of forensic post-mortem MR imaging in adults.

Authors:  T D Ruder; M J Thali; G M Hatch
Journal:  Br J Radiol       Date:  2014-04       Impact factor: 3.039

2.  Postmortem MR quantification of the heart for characterization and differentiation of ischaemic myocardial lesions.

Authors:  Wolf-Dieter Zech; Nicole Schwendener; Anders Persson; Marcel J Warntjes; Christian Jackowski
Journal:  Eur Radiol       Date:  2015-01-16       Impact factor: 5.315

3.  Temperature dependence of postmortem MR quantification for soft tissue discrimination.

Authors:  Wolf-Dieter Zech; Nicole Schwendener; Anders Persson; Marcel J Warntjes; Christian Jackowski
Journal:  Eur Radiol       Date:  2015-02-01       Impact factor: 5.315

Review 4.  Application of contrast media in post-mortem imaging (CT and MRI).

Authors:  Silke Grabherr; Jochen Grimm; Pia Baumann; Patrice Mangin
Journal:  Radiol Med       Date:  2015-04-05       Impact factor: 3.469

5.  Accuracy of targeted post-mortem computed tomography coronary angiography compared to assessment of serial histological sections.

Authors:  B Morgan; M J Biggs; J Barber; V Raj; J Amoroso; F E Hollingbury; C Robinson; G N Rutty
Journal:  Int J Legal Med       Date:  2012-11-10       Impact factor: 2.686

Review 6.  Postmortem cardiac magnetic resonance in sudden cardiac death.

Authors:  Benedetta Guidi; Giovanni Donato Aquaro; Marco Gesi; Michele Emdin; Marco Di Paolo
Journal:  Heart Fail Rev       Date:  2018-09       Impact factor: 4.214

7.  Differentiation of antemortem pulmonary thromboembolism and postmortem clot with unenhanced MRI: a case report.

Authors:  Ingo von Both; Silvio Giancarlo Bruni; Jayantha C Herath
Journal:  Forensic Sci Med Pathol       Date:  2018-01-04       Impact factor: 2.007

8.  T2 and T2 mapping in ex situ porcine myocardium: myocardial intravariability, temporal stability and the effects of complete coronary occlusion.

Authors:  Bridgette Webb; Martin Manninger; Marlene Leoni; Thomas Widek; Martin Dobrovnik; Daniel Scherr; Rudolf Stollberger; Thorsten Schwark
Journal:  Int J Legal Med       Date:  2019-12-18       Impact factor: 2.686

Review 9.  Postmortem imaging of sudden cardiac death.

Authors:  Katarzyna Michaud; Silke Grabherr; Christian Jackowski; Marc Daniel Bollmann; Franceso Doenz; Patrice Mangin
Journal:  Int J Legal Med       Date:  2013-01-16       Impact factor: 2.686

10.  Pulmonary thrombembolism as cause of death on unenhanced postmortem 3T MRI.

Authors:  Christian Jackowski; Silke Grabherr; Nicole Schwendener
Journal:  Eur Radiol       Date:  2012-12-16       Impact factor: 5.315

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