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Literature DB >> 2180148

Salmonella virulence: new clues to intramacrophage survival.

Abstract

Salmonella are capable of survival in macrophages (cells which have evolved specific mechanisms to kill pathogenic bacteria). One mechanism involves the bactericidal peptides called defensins which insert into phospholipid bilayers to generate transmembrane pores. Synthesis of the Salmonella gene products which determine resistance to defensins has been found to be under the control of a transcriptional regulatory protein termed PhoP.

Entities: Chemical Disease

Mesh：

Year: 1990 PMID： 2180148 DOI： 10.1016/0968-0004(90)90128-x

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

28 in total

Review 1. Heat-shock proteins and pathogenesis of bacterial infections.

Authors: S H Kaufmann
Journal: Springer Semin Immunopathol Date: 1991

2. Phenotypic and transcriptional characterization of the meningococcal PhoPQ system, a magnesium-sensing two-component regulatory system that controls genes involved in remodeling the meningococcal cell surface.

Authors: J Newcombe; J C Jeynes; E Mendoza; J Hinds; G L Marsden; R A Stabler; M Marti; J J McFadden
Journal: J Bacteriol Date: 2005-07 Impact factor: 3.490

Review 3. DNA topology and adaptation of Salmonella typhimurium to an intracellular environment.

Authors: D G Marshall; F Bowe; C Hale; G Dougan; C J Dorman
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2000-05-29 Impact factor: 6.237

4. Analysis of host cells associated with the Spv-mediated increased intracellular growth rate of Salmonella typhimurium in mice.

Authors: P A Gulig; T J Doyle; J A Hughes; H Matsui
Journal: Infect Immun Date: 1998-06 Impact factor: 3.441

10. Characterization of an avirulent pleiotropic mutant of the insect pathogen Bacillus thuringiensis: reduced expression of flagellin and phospholipases.

Authors: M Y Zhang; A Lövgren; M G Low; R Landén
Journal: Infect Immun Date: 1993-12 Impact factor: 3.441

Salmonella virulence: new clues to intramacrophage survival.

Review 1. Heat-shock proteins and pathogenesis of bacterial infections.

2. Phenotypic and transcriptional characterization of the meningococcal PhoPQ system, a magnesium-sensing two-component regulatory system that controls genes involved in remodeling the meningococcal cell surface.

Review 3. DNA topology and adaptation of Salmonella typhimurium to an intracellular environment.

4. Analysis of host cells associated with the Spv-mediated increased intracellular growth rate of Salmonella typhimurium in mice.

5. Involvement of signal transduction pathways in Salmonella typhimurium porin activated gut macrophages.

6. Infection with an avirulent phoP mutant of Neisseria meningitidis confers broad cross-reactive immunity.

7. Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon.

8. Characterization of a novel intracellularly activated gene from Salmonella enterica serovar typhi.

9. Role of acid tolerance response genes in Salmonella typhimurium virulence.

10. Characterization of an avirulent pleiotropic mutant of the insect pathogen Bacillus thuringiensis: reduced expression of flagellin and phospholipases.