Literature DB >> 21801078

Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites.

A Veršilovskis1, B Huybrecht, E K Tangni, L Pussemier, S De Saeger, A Callebaut.   

Abstract

Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, α-zearalenol, β-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.
© 2011 Taylor & Francis

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Year:  2011        PMID: 21801078     DOI: 10.1080/19440049.2011.603364

Source DB:  PubMed          Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess        ISSN: 1944-0057


  10 in total

1.  A QuEChERS-Based Liquid Chromatography-Tandem Mass Spectrometry Method for the Simultaneous Determination of Nine Zearalenone-Like Mycotoxins in Pigs.

Authors:  Zheng Yan; Lan Wang; Jun Wang; Yanglan Tan; Dianzhen Yu; Xiaojiao Chang; Yingying Fan; Duoyong Zhao; Cheng Wang; Marthe De Boevre; Sarah De Saeger; Changpo Sun; Aibo Wu
Journal:  Toxins (Basel)       Date:  2018-03-20       Impact factor: 4.546

2.  Hydrolytic Fate of 3/15-Acetyldeoxynivalenol in Humans: Specific Deacetylation by the Small Intestine and Liver Revealed Using in Vitro and ex Vivo Approaches.

Authors:  El Hassan Ajandouz; Stéphane Berdah; Vincent Moutardier; Thierry Bege; David Jérémie Birnbaum; Josette Perrier; Eric Di Pasquale; Marc Maresca
Journal:  Toxins (Basel)       Date:  2016-07-28       Impact factor: 4.546

3.  Cross-reactivity features of deoxynivalenol (DON)-targeted immunoaffinity columns aiming to achieve simultaneous analysis of DON and major conjugates in cereal samples.

Authors:  Carlos Gonçalves; Joerg Stroka
Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess       Date:  2016-05-31

4.  Simultaneous Determination of Deoxynivalenol, Its Modified Forms, Nivalenol and Fusarenone-X in Feedstuffs by the Liquid Hromatography-Tandem Mass Spectrometry Method.

Authors:  Łukasz Panasiuk; Piotr Jedziniak; Katarzyna Pietruszka; Andrzej Posyniak
Journal:  Toxins (Basel)       Date:  2020-06-01       Impact factor: 4.546

5.  Zearalenone and Metabolites in Livers of Turkey Poults and Broiler Chickens Fed with Diets Containing Fusariotoxins.

Authors:  Didier Tardieu; Angelique Travel; Jean-Paul Metayer; Celeste Le Bourhis; Philippe Guerre
Journal:  Toxins (Basel)       Date:  2020-08-15       Impact factor: 4.546

Review 6.  Immunoaffinity Extraction and Alternative Approaches for the Analysis of Toxins in Environmental, Food or Biological Matrices.

Authors:  Nathalie Delaunay; Audrey Combès; Valérie Pichon
Journal:  Toxins (Basel)       Date:  2020-12-13       Impact factor: 4.546

Review 7.  LC-MS/MS-based multibiomarker approaches for the assessment of human exposure to mycotoxins.

Authors:  Benedikt Warth; Michael Sulyok; Rudolf Krska
Journal:  Anal Bioanal Chem       Date:  2013-06-18       Impact factor: 4.142

Review 8.  Masked mycotoxins: a review.

Authors:  Franz Berthiller; Colin Crews; Chiara Dall'Asta; Sarah De Saeger; Geert Haesaert; Petr Karlovsky; Isabelle P Oswald; Walburga Seefelder; Gerrit Speijers; Joerg Stroka
Journal:  Mol Nutr Food Res       Date:  2012-10-10       Impact factor: 5.914

9.  Development and evaluation of monoclonal antibodies for the glucoside of T-2 toxin (t2-glc).

Authors:  Chris M Maragos; Cletus Kurtzman; Mark Busman; Neil Price; Susan McCormick
Journal:  Toxins (Basel)       Date:  2013-07-19       Impact factor: 4.546

10.  Synthesis of zearalenone-16-β,D-glucoside and zearalenone-16-sulfate: A tale of protecting resorcylic acid lactones for regiocontrolled conjugation.

Authors:  Hannes Mikula; Julia Weber; Dennis Svatunek; Philipp Skrinjar; Gerhard Adam; Rudolf Krska; Christian Hametner; Johannes Fröhlich
Journal:  Beilstein J Org Chem       Date:  2014-05-15       Impact factor: 2.883

  10 in total

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