Literature DB >> 21799601

Authors' reply.

Ravindra B Kamble1, Roshan V Shetty, N Diwakar, G Madhusudan.   

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Year:  2011        PMID: 21799601      PMCID: PMC3137856     

Source DB:  PubMed          Journal:  Indian J Radiol Imaging        ISSN: 0970-2016


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Dear Sir, We agree with Parihar et al.[1] that this technique of MRI lymphangiography is relatively noninvasive and useful in depicting lymphatic channels of the lower limb in secondary lymphedema with the added advantages of absence of radiation, multiplanar reconstruction, and precise compartmental localization.[2] We have used gadopentate dimeglumine (Magnevist, Bayer Schering Pharma, Berlin, Germany) for injection which is different from gadobenate dimeglumine (MultiHance, Bracco, Milano, Italy); Magnevist has low viscosity (2.9 vs 5.3) and low T1 relaxivity (4.1 vs 8.3 at 1.5T) as compared to Multihance.[34] We were not able to demonstrate inguinal lymph nodes probably because Magnevist gets washed away early as it reaches the groin due to low viscosity and low relaxivity. We completely agree with the authors that newer contrast media like Multihance may be a better option to visualize lymphatic channels along with visualization of inguinal lymph nodes in secondary lymphedema due to the higher relaxivity, which may help improve the quality of the technique.
  4 in total

Review 1.  Safety of magnetic resonance contrast media.

Authors:  V M Runge
Journal:  Top Magn Reson Imaging       Date:  2001-08

Review 2.  Contrast agents for magnetic resonance imaging: safety update.

Authors:  Miles A Kirchin; Val M Runge
Journal:  Top Magn Reson Imaging       Date:  2003-10

3.  Technical note: MRI lymphangiography of the lower limb in secondary lymphedema.

Authors:  Ravindra B Kamble; Roshan Shetty; N Diwakar; G Madhusudan
Journal:  Indian J Radiol Imaging       Date:  2011-01

4.  Interstitial MRI lymphangiography of the lower limbs.

Authors:  Anit Parihar; Swastika Suvirya; Suresh Kumar; Ragini Singh
Journal:  Indian J Radiol Imaging       Date:  2011-04
  4 in total

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