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Literature DB >> 21799505

The complex world of kidney microRNAs.

Balakuntalam S Kasinath¹, Denis Feliers.

Abstract

MicroRNAs are short noncoding RNAs that usually reduce translation of messenger RNAs. Changes in microRNA-192 (miR-192) are reported in states of renal fibrosis. New evidence supports a role for miR-192 and its target miR-200b/c in transforming growth factor-β1 regulation of its own expression and that of collagens in mesangial cells, with a possible role in diabetic nephropathy. As there is controversy on the role of these microRNAs in diabetic nephropathy, more work is needed.

Entities: Disease Gene

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Year: 2011 PMID： 21799505 DOI： 10.1038/ki.2011.165

Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612

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Cited

21 in total

1. Molecular events in matrix protein metabolism in the aging kidney.

Authors: Kavithalakshmi Sataranatarajan; Denis Feliers; Meenalakshmi M Mariappan; Hak Joo Lee; Myung Ja Lee; Robert T Day; Hima Bindu Yalamanchili; Goutam G Choudhury; Jeffrey L Barnes; Holly Van Remmen; Arlan Richardson; Balakuntalam S Kasinath
Journal: Aging Cell Date: 2012-10-19 Impact factor: 9.304

2. Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion.

Authors: Amit Bera; Falguni Das; Nandini Ghosh-Choudhury; Meenalakshmi M Mariappan; Balakuntalam S Kasinath; Goutam Ghosh Choudhury
Journal: Am J Physiol Cell Physiol Date: 2017-07-12 Impact factor: 4.249

Review 3. Epigenetics in Kidney Transplantation: Current Evidence, Predictions, and Future Research Directions.

Authors: Valeria R Mas; Thu H Le; Daniel G Maluf
Journal: Transplantation Date: 2016-01 Impact factor: 4.939

4. High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery.

Authors: Yi-Chun Tsai; Mei-Chuan Kuo; Wei-Wen Hung; Ling-Yu Wu; Ping-Hsun Wu; Wei-An Chang; Po-Lin Kuo; Ya-Ling Hsu
Journal: Mol Ther Date: 2020-01-15 Impact factor: 11.454

5. MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy.

Authors: Kenichi Koga; Hideki Yokoi; Kiyoshi Mori; Masato Kasahara; Takashige Kuwabara; Hirotaka Imamaki; Akira Ishii; Keita P Mori; Yukiko Kato; Shoko Ohno; Naohiro Toda; Moin A Saleem; Akira Sugawara; Kazuwa Nakao; Motoko Yanagita; Masashi Mukoyama
Journal: Diabetologia Date: 2015-06-11 Impact factor: 10.122

6. Astragaloside IV attenuates renal fibrosis through repressing epithelial-to-mesenchymal transition by inhibiting microRNA-192 expression: in vivo and in vitro studies.

Authors: Yaochen Cao; Li Zhang; Yu Wang; Qingchun Fan; Yakun Cong
Journal: Am J Transl Res Date: 2019-08-15 Impact factor: 4.060

The complex world of kidney microRNAs.

1. Molecular events in matrix protein metabolism in the aging kidney.

2. Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion.

Review 3. Epigenetics in Kidney Transplantation: Current Evidence, Predictions, and Future Research Directions.

4. High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery.

5. MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy.

6. Astragaloside IV attenuates renal fibrosis through repressing epithelial-to-mesenchymal transition by inhibiting microRNA-192 expression: in vivo and in vitro studies.

7. TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy.

Review 8. Molecular targets for treatment of kidney fibrosis.

9. MicroRNAs in HIV-associated nephropathy (HIVAN).

Review 10. Role of regulatory micro RNAs in type 2 diabetes mellitus-related inflammation.