Literature DB >> 21797808

Factors affecting adherence to treatment of psoriasis: comparing biologic therapy to other modalities.

Sue Ann Chan1, Fawad Hussain, Linda G Lawson, Anthony D Ormerod.   

Abstract

OBJECTIVES: This study evaluated self-reported patient adherence to different types of treatment in psoriasis and factors that affect adherence. PATIENTS AND METHODS: Patients attending a Dermatology Department for treatments of psoriasis completed a questionnaire about adherence to each of their therapies, Self-assessed Psoriasis Area and Severity Index (SAPASI) and Dermatology Life Quality Index (DLQI).
RESULTS: Hundred and six patients participated, 98 on topical treatments, 43 on oral systemic therapies, 39 on phototherapy and 29 were on biologic therapies. The overall rate of self-reported treatment adherence was 85.8%. There was a significant relationship between the types of treatment (topical, oral systemic, phototherapy and biologic therapy) and the number of combinations of treatments and adherence. Adherence ranked significantly better on biologic therapies 100%, followed by oral therapy 96%, phototherapy 93% and then topical therapy 75%. Being too busy, being fed up and cigarette smoking were associated with reduced adherence. About 56.8% of patients reported that messiness of treatment prevented them from adhering. Patients with mild psoriasis and those with DLQI of 5 or less adhered less to topical therapy.
CONCLUSIONS: There is a significant relationship between the types of treatment (topical, oral systemic, phototherapy and biologic therapy) and the number of combinations of treatments and adherence.

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Year:  2011        PMID: 21797808     DOI: 10.3109/09546634.2011.607425

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  17 in total

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9.  Group-based trajectory modeling to assess adherence to biologics among patients with psoriasis.

Authors:  Yunfeng Li; Huanxue Zhou; Beilei Cai; Kristijan H Kahler; Haijun Tian; Susan Gabriel; Steve Arcona
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10.  Can an app supporting psoriasis patients improve adherence to topical treatment? A single-blind randomized controlled trial.

Authors:  Mathias Tiedemann Svendsen; Flemming Andersen; Kirsten Hammond Andersen; Klaus Ejner Andersen
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