| Literature DB >> 21796518 |
Diping Wang1, Donald J Tindall.
Abstract
Androgens are critical for normal prostate development and function, as well as prostate cancer initiation and progression. Androgens function mainly by regulating target gene expression through the androgen receptor (AR). Many studies have shown that androgen-AR signaling exerts actions on key events during prostate carcinogenesis. In this review, androgen action in distinct aspects of prostate carcinogenesis, including (i) cell proliferation, (ii) cell apoptosis, and (iii) prostate cancer metastasis will be discussed.Entities:
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Year: 2011 PMID： 21796518 DOI： 10.1007/978-1-61779-243-4_2
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745