The possible molecular evolution of sapoviruses by inter- and intra-genogroup recombination.

Sapporo virus belongs to the genus Sapovirus (family Caliciviridae) and has a non-segmented single-stranded, positive-sense RNA genome. This virus causes acute gastroenteritis in human, porcine and mink hosts. In this study, the complete genome of a Brazilian sapovirus isolate from a child with acute gastroenteritis was determined. A phylogenetic tree was constructed to analyze the genotype of this sapovirus (Sapo_BR-DF01), and possible intra- and inter-genogroups recombination events were evaluated in silico using the RDP3 program. Two inter-genogroup and two intra-genogroup recombination events were newly recognized in this study.