| Literature DB >> 21793562 |
Yohei Adachi1, Noriyuki Kamei, Satoshi Yokoshima, Tohru Fukuyama.
Abstract
A total synthesis of (-)-histrionicotoxin was achieved. Our synthesis features preparation of a pseudosymmetrical dienyne through chirality transfer from an allenylsilane, a dienyne metathesis to produce the bicyclo [5.4.0] system in optically active form, selective functionalization of a diene via a 5-exo-trig iodoetherification, and an asymmetric propargylation.Entities:
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Year: 2011 PMID： 21793562 DOI： 10.1021/ol2018032
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005