| Literature DB >> 21793533 |
Changwei Shao1, Xinyan Wang, Qun Zhang, Sheng Luo, Jichen Zhao, Yuefei Hu.
Abstract
In this novel acid-base jointly promoted CuAAC, the combination of CuI/DIPEA/HOAc was developed as a highly efficient catalytic system. The functions of DIPEA and HOAc have been assigned, and HOAc was recognized to accelerate the conversions of the C-Cu bond-containing intermediates and buffer the basicity of DIPEA. As a result, all drawbacks occurring in the popular catalytic system CuI/NR(3) were overcome easily.Entities:
Year: 2011 PMID: 21793533 DOI: 10.1021/jo200869a
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354