Literature DB >> 21791596

Long-term changes of the anterior corneal topography after photorefractive keratectomy for myopia and myopic astigmatism.

Marco Lombardo1, Giuseppe Lombardo, Pietro Ducoli, Sebastiano Serrao.   

Abstract

PURPOSE: To analyze the anterior corneal topography changes after 8 years after photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism.
METHODS: Sixty-six eyes (33 patients) underwent PRK using an excimer laser platform. Patients were subdivided into three groups: the low myopia (13 patients; range, -1.25 to -4.40 diopters [D]), the high myopia (13 patients; -4.50 to -9.00 D), and astigmatism (7 patients; cylinder component between -2.00 and -5.00 D) groups. The preoperative and 1-, 2-, 4-, 6-, and 8-year postoperative average corneal maps were computed for each study group. Changes inside and outside the optical zone, which was 6.00 mm in diameter for all eyes, during follow-up were further investigated.
RESULTS: The topographic central region, 2.00-mm diameter, was almost stable in all study groups, with changes < 0.39 D between 1 and 8 years. The postoperative variations at the peripheral region, 6.00- to 8.00-mm diameter, were related to the type and amount of refractive correction: a higher flattening (P < 0.05) has been assessed in the high-myopia group (-0.85 D) in comparison with the low-myopia group (-0.42 D) between 1 and 8 years. On the contrary, corneal periphery steepened (+2.22 D; P < 0.05) in the astigmatism group during follow-up, mainly at the superior and inferior emimeridians.
CONCLUSIONS: The anterior corneal topography continues to change configuration even long term after PRK. Changes are confined outside the functional optical zone of the cornea. PRK for the correction of myopia was shown not to influence the mechanical stability of the corneal tissue at 8 years after surgery.

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Year:  2011        PMID: 21791596     DOI: 10.1167/iovs.10-7052

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  3 in total

1.  Analysis of the viscoelastic properties of the human cornea using Scheimpflug imaging in inflation experiment of eye globes.

Authors:  Giuseppe Lombardo; Sebastiano Serrao; Marianna Rosati; Marco Lombardo
Journal:  PLoS One       Date:  2014-11-14       Impact factor: 3.240

2.  Twenty-Year Follow-Up of Excimer Laser Photorefractive Keratectomy: A Retrospective Observational Study.

Authors:  Giovanni Cennamo; Feliciana Menna; Fabrizio Sinisi; Gilda Cennamo; Maria Angelica Breve; Pasquale Napolitano; Maddalena De Bernardo; Livio Vitiello; Nicola Rosa
Journal:  Ophthalmol Ther       Date:  2020-07-28

3.  The results of photorefractive keratectomy with Mitomycin-C in myopia correction after 5 years.

Authors:  Masih Hashemi; Mohammad Aghazadeh Amiri; Mehdi Tabatabaee; Ali Ayatollahi
Journal:  Pak J Med Sci       Date:  2016 Jan-Feb       Impact factor: 1.088

  3 in total

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