| Literature DB >> 21789300 |
Delphine Sicard1, Samy Cecioni, Maksym Iazykov, Yann Chevolot, Susan E Matthews, Jean-Pierre Praly, Eliane Souteyrand, Anne Imberty, Sébastien Vidal, Magali Phaner-Goutorbe.
Abstract
Atomic force microscopy reveals that Pseudomonas aeruginosa LecA (PA-IL) and a tetra-galactosylated 1,3-alternate calix[4]arene-based glycocluster self-assemble according to an aggregative chelate binding mode to create monodimensional filaments. Lectin oligomers are identified along the filaments and defects in chelate binding generate branches and bifurcations. A molecular model with alternate 90° orientation of LecA tetramers is proposed to describe the organisation of lectins and glycoclusters in the filaments. This journal is © The Royal Society of Chemistry 2011Entities:
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Year: 2011 PMID： 21789300 DOI： 10.1039/c1cc13097h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222