Literature DB >> 21788949

GSK3 inhibitors enhance retinoic acid receptor activity and induce the differentiation of retinoic acid-sensitive myeloid leukemia cells.

J Si, L Mueller, S J Collins.   

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Year:  2011        PMID： 21788949     DOI： 10.1038/leu.2011.171

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  18 in total

1.  An ATRActive future for differentiation therapy in AML.

Authors:  Daniel E Johnson; Robert L Redner
Journal:  Blood Rev       Date:  2015-01-21       Impact factor: 8.250

2.  Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.

Authors:  Florence F Wagner; Lina Benajiba; Arthur J Campbell; Michel Weïwer; Joshua R Sacher; Jennifer P Gale; Linda Ross; Alexandre Puissant; Gabriela Alexe; Amy Conway; Morgan Back; Yana Pikman; Ilene Galinsky; Daniel J DeAngelo; Richard M Stone; Taner Kaya; Xi Shi; Matthew B Robers; Thomas Machleidt; Jennifer Wilkinson; Olivier Hermine; Andrew Kung; Adam J Stein; Damodharan Lakshminarasimhan; Michael T Hemann; Edward Scolnick; Yan-Ling Zhang; Jen Q Pan; Kimberly Stegmaier; Edward B Holson
Journal:  Sci Transl Med       Date:  2018-03-07       Impact factor: 17.956

3.  Lithium chloride antileukemic activity in acute promyelocytic leukemia is GSK-3 and MEK/ERK dependent.

Authors:  F Zassadowski; K Pokorna; N Ferre; F Guidez; L Llopis; O Chourbagi; M Chopin; J Poupon; P Fenaux; R Ann Padua; M Pla; C Chomienne; B Cassinat
Journal:  Leukemia       Date:  2015-06-25       Impact factor: 11.528

4.  GSK-3 Inhibition Sensitizes Acute Myeloid Leukemia Cells to 1,25D-Mediated Differentiation.

Authors:  Kalpana Gupta; Tammy Stefan; James Ignatz-Hoover; Stephen Moreton; Gary Parizher; Yogen Saunthararajah; David N Wald
Journal:  Cancer Res       Date:  2016-03-10       Impact factor: 12.701

5.  GSK3 is a regulator of RAR-mediated differentiation.

Authors:  K Gupta; F Gulen; L Sun; R Aguilera; A Chakrabarti; J Kiselar; M K Agarwal; D N Wald
Journal:  Leukemia       Date:  2012-01-06       Impact factor: 11.528

6.  Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation.

Authors:  Nina Orfali; Tracey R O'Donovan; Michelle J Nyhan; Adrian Britschgi; Mario P Tschan; Mary R Cahill; Nigel P Mongan; Lorraine J Gudas; Sharon L McKenna
Journal:  Exp Hematol       Date:  2015-05-16       Impact factor: 3.084

Review 7.  Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer.

Authors:  Amy Walz; Andrey Ugolkov; Sunandana Chandra; Alan Kozikowski; Benedito A Carneiro; Thomas V O'Halloran; Francis J Giles; Daniel D Billadeau; Andrew P Mazar
Journal:  Clin Cancer Res       Date:  2017-01-04       Impact factor: 12.531

8.  A Novel Glycogen Synthase Kinase-3 Inhibitor Optimized for Acute Myeloid Leukemia Differentiation Activity.

Authors:  Sophia Hu; Masumi Ueda; Lindsay Stetson; James Ignatz-Hoover; Stephen Moreton; Amit Chakrabarti; Zhiqiang Xia; Goutam Karan; Marcos de Lima; Mukesh K Agrawal; David N Wald
Journal:  Mol Cancer Ther       Date:  2016-05-09       Impact factor: 6.261

9.  Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin.

Authors:  Urmila Maitra; Liwu Li
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-11-01       Impact factor: 8.311

10.  Sorafenib Inhibition of Mcl-1 Accelerates ATRA-Induced Apoptosis in Differentiation-Responsive AML Cells.

Authors:  Rui Wang; Lijuan Xia; Janice Gabrilove; Samuel Waxman; Yongkui Jing
Journal:  Clin Cancer Res       Date:  2015-10-12       Impact factor: 12.531
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