Literature DB >> 2178699

Estrogen effects on the synaptology and neural membranes of the rat hypothalamic arcuate nucleus.

F Naftolin1, L M Garcia-Segura, D Keefe, C Leranth, N J Maclusky, J R Brawer.   

Abstract

The concept of estrogen-induced "sexual differentiation of the brain" has been a useful focus for investigation. However, it has become clear that the action of estrogen on the rat brain is lifelong, including effects on neurogenesis in the fetus, synaptogenesis in the newborn, and synaptic remodeling in the adult. Estrogen imparts sex differences in the rat's brain by shaping synaptology, postsynaptic membranes, and glia within the arcuate nucleus. These effects of estrogen on the arcuate nucleus also could underlie sexual maturation in both sexes and the development of senescent constant estrus in females.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2178699     DOI： 10.1095/biolreprod42.1.21

Source DB:  PubMed          Journal:  Biol Reprod        ISSN： 0006-3363            Impact factor:   4.285


  12 in total

Review 1.  Developmental specification of metabolic circuitry.

Authors:  Amanda E Elson; Richard B Simerly
Journal:  Front Neuroendocrinol       Date:  2015-09-25       Impact factor: 8.606

Review 2.  Estrogen effects on neuronal morphology.

Authors:  Sonsoles de Lacalle
Journal:  Endocrine       Date:  2006-04       Impact factor: 3.633

3.  Immunohistochemical localization of estrogen receptors within aromatase-immunoreactive neurons in the fetal and neonatal rat brain.

Authors:  Y Tsuruo; K Ishimura; S Hayashi; Y Osawa
Journal:  Anat Embryol (Berl)       Date:  1996-02

Review 4.  Potential neuronal mechanisms of estrogen actions in synaptogenesis and synaptic plasticity.

Authors:  F Naftolin; C Leranth; T L Horvath; L M Garcia-Segura
Journal:  Cell Mol Neurobiol       Date:  1996-04       Impact factor: 5.046

5.  Anatomical distribution and cellular basis for high levels of aromatase activity in the brain of teleost fish: aromatase enzyme and mRNA expression identify glia as source.

Authors:  P M Forlano; D L Deitcher; D A Myers; A H Bass
Journal:  J Neurosci       Date:  2001-11-15       Impact factor: 6.167

6.  Neuroplastic changes in the hypothalamic arcuate nucleus: the estradiol effect is accompanied by increased exoendocytotic activity of neuronal membranes.

Authors:  A Párducz; T Szilágyi; S Hoyk; F Naftolin; L M Garcia-Segura
Journal:  Cell Mol Neurobiol       Date:  1996-04       Impact factor: 5.046

Review 7.  Gender-specific steroid metabolism in neural differentiation.

Authors:  J B Hutchison
Journal:  Cell Mol Neurobiol       Date:  1997-12       Impact factor: 5.046

Review 8.  Sexual differentiation of the brain: genes, estrogen, and neurotrophic factors.

Authors:  Hugo F Carrer; María J Cambiasso
Journal:  Cell Mol Neurobiol       Date:  2002-12       Impact factor: 5.046

Review 9.  Testosterone and progesterone metabolism in the central nervous system: cellular localization and mechanism of control of the enzymes involved.

Authors:  L Martini; F Celotti; R C Melcangi
Journal:  Cell Mol Neurobiol       Date:  1996-06       Impact factor: 5.046

10.  Correlations among brain gray matter volumes, age, gender, and hemisphere in healthy individuals.

Authors:  Yasuyuki Taki; Benjamin Thyreau; Shigeo Kinomura; Kazunori Sato; Ryoi Goto; Ryuta Kawashima; Hiroshi Fukuda
Journal:  PLoS One       Date:  2011-07-27       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.