Literature DB >> 21785853

Celecoxib for recurrent sclerouveitis after syphilitic panuveitis. A case report.

Ana M Suelves1, Sebastián Martinez-Castillo, Miguel Salavert, Manuel Díaz-Llopis.   

Abstract

PURPOSE: To report a case of recurrent ocular inflammation after optimal therapy of bilateral syphilitic panuveitis responding to oral celecoxib.
METHODS: A case report was conducted.
RESULTS: A 76-year-old man presented with painful blurry vision in both eyes. Ocular examination disclosed bilateral panuveitis. Serological testing confirmed blood and cerebrospinal fluid syphilitic involvement. After 2 weeks of intravenous penicillin therapy, recurrent episodic sclerouveitis was observed.
CONCLUSION: Ocular inflammation after healing of infectious uveitis is a rare ophthalmic sequela. In an immunocompetent patient, either re-infection or immune uveitis should be evoked. Non-steroidal therapeutic options, as celecoxib, could be a good option of treatment in such immune cases.

Entities:  

Year:  2011        PMID: 21785853      PMCID: PMC3223351          DOI: 10.1007/s12348-011-0031-0

Source DB:  PubMed          Journal:  J Ophthalmic Inflamm Infect        ISSN: 1869-5760


  5 in total

1.  Saving the vision of children with juvenile rheumatoid arthritis-associated uveitis.

Authors:  Q D Nguyen; C S Foster
Journal:  JAMA       Date:  1998-10-07       Impact factor: 56.272

Review 2.  Syphilitic uveitis: a review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients.

Authors:  Bhagya Chathri Amaratunge; Jayne E Camuglia; Anthony J Hall
Journal:  Clin Exp Ophthalmol       Date:  2010-01       Impact factor: 4.207

Review 3.  Syphilis: reemergence of an old adversary.

Authors:  Jennifer R Chao; Rahul N Khurana; Amani A Fawzi; Harsha S Reddy; Narsing A Rao
Journal:  Ophthalmology       Date:  2006-08-28       Impact factor: 12.079

4.  Nonsteroidal anti-inflammatory therapy and recurrent acute anterior uveitis.

Authors:  Vanessa M B Fiorelli; Pooja Bhat; C Stephen Foster
Journal:  Ocul Immunol Inflamm       Date:  2010-04       Impact factor: 3.070

Review 5.  Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids.

Authors:  Nicolas W J Schröder; Jana Eckert; Gunthard Stübs; Ralf R Schumann
Journal:  Immunobiology       Date:  2008-01-02       Impact factor: 3.144

  5 in total

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