Literature DB >> 21785575

Learning Hidden Markov Models for Regression using Path Aggregation.

Keith Noto1, Mark Craven.   

Abstract

We consider the task of learning mappings from sequential data to real-valued responses. We present and evaluate an approach to learning a type of hidden Markov model (HMM) for regression. The learning process involves inferring the structure and parameters of a conventional HMM, while simultaneously learning a regression model that maps features that characterize paths through the model to continuous responses. Our results, in both synthetic and biological domains, demonstrate the value of jointly learning the two components of our approach.

Entities:  

Year:  2008        PMID: 21785575      PMCID: PMC3141580     

Source DB:  PubMed          Journal:  Uncertain Artif Intell        ISSN: 1525-3384


  12 in total

1.  The spectrum kernel: a string kernel for SVM protein classification.

Authors:  Christina Leslie; Eleazar Eskin; William Stafford Noble
Journal:  Pac Symp Biocomput       Date:  2002

2.  The UCSC Table Browser data retrieval tool.

Authors:  Donna Karolchik; Angela S Hinrichs; Terrence S Furey; Krishna M Roskin; Charles W Sugnet; David Haussler; W James Kent
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

3.  CisModule: de novo discovery of cis-regulatory modules by hierarchical mixture modeling.

Authors:  Qing Zhou; Wing H Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-05       Impact factor: 11.205

4.  Learning probabilistic models of cis-regulatory modules that represent logical and spatial aspects.

Authors:  Keith Noto; Mark Craven
Journal:  Bioinformatics       Date:  2007-01-15       Impact factor: 6.937

5.  Genomic expression programs in the response of yeast cells to environmental changes.

Authors:  A P Gasch; P T Spellman; C M Kao; O Carmel-Harel; M B Eisen; G Storz; D Botstein; P O Brown
Journal:  Mol Biol Cell       Date:  2000-12       Impact factor: 4.138

6.  Integrating regulatory motif discovery and genome-wide expression analysis.

Authors:  Erin M Conlon; X Shirley Liu; Jason D Lieb; Jun S Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-07       Impact factor: 11.205

7.  Prediction of complete gene structures in human genomic DNA.

Authors:  C Burge; S Karlin
Journal:  J Mol Biol       Date:  1997-04-25       Impact factor: 5.469

8.  Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment.

Authors:  C E Lawrence; S F Altschul; M S Boguski; J S Liu; A F Neuwald; J C Wootton
Journal:  Science       Date:  1993-10-08       Impact factor: 47.728

9.  Hidden Markov models in computational biology. Applications to protein modeling.

Authors:  A Krogh; M Brown; I S Mian; K Sjölander; D Haussler
Journal:  J Mol Biol       Date:  1994-02-04       Impact factor: 5.469

10.  Analysis of computational approaches for motif discovery.

Authors:  Nan Li; Martin Tompa
Journal:  Algorithms Mol Biol       Date:  2006-05-19       Impact factor: 1.405

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