Literature DB >> 21785120

Thimerosal exposure in early life and neuropsychological outcomes 7-10 years later.

John P Barile1, Gabriel P Kuperminc, Eric S Weintraub, Jonathan W Mink, William W Thompson.   

Abstract

OBJECTIVE: The authors used a public use data set to investigate associations between the receipt of thimerosal-containing vaccines and immune globulins early in life and neuropsychological outcomes assessed at 7-10 years.
METHODS: The data were originally created by evaluating 1,047 children ages 7-10 years and their biological mothers. This study developed seven latent neuropsychological factors and regressed them on a comprehensive set of covariates and thimerosal exposure variables.
RESULTS: The authors found no statistically significant associations between thimerosal exposure from vaccines early in life and six of the seven latent constructs. There was a small, but statistically significant association between early thimerosal exposure and the presence of tics in boys.
CONCLUSIONS: This finding should be interpreted with caution due to limitations in the measurement of tics and the limited biological plausibility regarding a causal relationship.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21785120     DOI: 10.1093/jpepsy/jsr048

Source DB:  PubMed          Journal:  J Pediatr Psychol        ISSN: 0146-8693


  10 in total

Review 1.  Abating Mercury Exposure in Young Children Should Include Thimerosal-Free Vaccines.

Authors:  José G Dórea
Journal:  Neurochem Res       Date:  2017-04-24       Impact factor: 3.996

2.  Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology.

Authors:  Bharathi S Gadad; Wenhao Li; Umar Yazdani; Stephen Grady; Trevor Johnson; Jacob Hammond; Howard Gunn; Britni Curtis; Chris English; Vernon Yutuc; Clayton Ferrier; Gene P Sackett; C Nathan Marti; Keith Young; Laura Hewitson; Dwight C German
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-28       Impact factor: 11.205

Review 3.  Neuropathology and animal models of autism: genetic and environmental factors.

Authors:  Bharathi S Gadad; Laura Hewitson; Keith A Young; Dwight C German
Journal:  Autism Res Treat       Date:  2013-09-16

4.  Examination of the safety of pediatric vaccine schedules in a non-human primate model: assessments of neurodevelopment, learning, and social behavior.

Authors:  Britni Curtis; Noelle Liberato; Megan Rulien; Kelly Morrisroe; Caroline Kenney; Vernon Yutuc; Clayton Ferrier; C Nathan Marti; Dorothy Mandell; Thomas M Burbacher; Gene P Sackett; Laura Hewitson
Journal:  Environ Health Perspect       Date:  2015-02-18       Impact factor: 9.031

Review 5.  Methodological issues and evidence of malfeasance in research purporting to show thimerosal in vaccines is safe.

Authors:  Brian Hooker; Janet Kern; David Geier; Boyd Haley; Lisa Sykes; Paul King; Mark Geier
Journal:  Biomed Res Int       Date:  2014-06-04       Impact factor: 3.411

6.  Thimerosal exposure and increased risk for diagnosed tic disorder in the United States: a case-control study.

Authors:  David A Geier; Janet K Kern; Brian S Hooker; Paul G King; Lisa K Sykes; Kristin G Homme; Mark R Geier
Journal:  Interdiscip Toxicol       Date:  2015-06

Review 7.  Thimerosal exposure and the role of sulfation chemistry and thiol availability in autism.

Authors:  Janet K Kern; Boyd E Haley; David A Geier; Lisa K Sykes; Paul G King; Mark R Geier
Journal:  Int J Environ Res Public Health       Date:  2013-08-20       Impact factor: 3.390

8.  Adverse events following immunization with vaccines containing adjuvants.

Authors:  S Cerpa-Cruz; P Paredes-Casillas; E Landeros Navarro; A G Bernard-Medina; G Martínez-Bonilla; S Gutiérrez-Ureña
Journal:  Immunol Res       Date:  2013-07       Impact factor: 4.505

9.  Suppression by thimerosal of ex-vivo CD4+ T cell response to influenza vaccine and induction of apoptosis in primary memory T cells.

Authors:  Emily Loison; Béatrice Poirier-Beaudouin; Valérie Seffer; Audrey Paoletti; Vered Abitbol; Eric Tartour; Odile Launay; Marie-Lise Gougeon
Journal:  PLoS One       Date:  2014-04-01       Impact factor: 3.240

10.  Microbial structure and function in infant and juvenile rhesus macaques are primarily affected by age, not vaccination status.

Authors:  Yu Hasegawa; Britni Curtis; Vernon Yutuc; Megan Rulien; Kelly Morrisroe; Kristin Watkins; Clayton Ferrier; Chris English; Laura Hewitson; Carolyn M Slupsky
Journal:  Sci Rep       Date:  2018-10-26       Impact factor: 4.379

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.