Literature DB >> 21784998

Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.

Lorina G Baker1, Charles A Specht, Jennifer K Lodge.   

Abstract

Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan. Multiple genetic approaches have defined a chitosan-deficient syndrome that includes slow growth and decreased cell integrity. Here we demonstrate chitosan is necessary for virulence and persistence in the mammalian host.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21784998      PMCID： PMC3187048          DOI： 10.1128/EC.05138-11

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


  24 in total

Review 1.  Fungal cell wall chitinases and glucanases.

Authors:  David J Adams
Journal:  Microbiology (Reading)       Date:  2004-07       Impact factor: 2.777

Review 2.  Mucor dimorphism.

Authors:  M Orlowski
Journal:  Microbiol Rev       Date:  1991-06

Review 3.  Cell wall chemistry, morphogenesis, and taxonomy of fungi.

Authors:  S Bartnicki-Garcia
Journal:  Annu Rev Microbiol       Date:  1968       Impact factor: 15.500

4.  A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans.

Authors:  Isaac R Banks; Charles A Specht; Maureen J Donlin; Kimberly J Gerik; Stuart M Levitz; Jennifer K Lodge
Journal:  Eukaryot Cell       Date:  2005-11

Review 5.  Clinical efficacy of new antifungal agents.

Authors:  Carol A Kauffman
Journal:  Curr Opin Microbiol       Date:  2006-08-09       Impact factor: 7.934

Review 6.  Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS.

Authors:  Benjamin J Park; Kathleen A Wannemuehler; Barbara J Marston; Nelesh Govender; Peter G Pappas; Tom M Chiller
Journal:  AIDS       Date:  2009-02-20       Impact factor: 4.177

7.  Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence.

Authors:  Y C Chang; K J Kwon-Chung
Journal:  Mol Cell Biol       Date:  1994-07       Impact factor: 4.272

8.  Production and isolation of chitosan from Mucor rouxii.

Authors:  S A White; P R Farina; I Fulton
Journal:  Appl Environ Microbiol       Date:  1979-08       Impact factor: 4.792

9.  Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans.

Authors:  S D Salas; J E Bennett; K J Kwon-Chung; J R Perfect; P R Williamson
Journal:  J Exp Med       Date:  1996-08-01       Impact factor: 14.307

10.  Pulmonary cryptococcosis induces chitinase in the rat.

Authors:  Alfin G Vicencio; Swati Narain; Zhongfang Du; Wang Yong Zeng; James Ritch; Arturo Casadevall; David L Goldman
Journal:  Respir Res       Date:  2008-05-15
View more
  46 in total

1.  Unique subsite specificity and potential natural function of a chitosan deacetylase from the human pathogen Cryptococcus neoformans.

Authors:  Lea Hembach; Martin Bonin; Christian Gorzelanny; Bruno M Moerschbacher
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-03       Impact factor: 11.205

2.  Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis.

Authors:  Ying-Lien Chen; Shang-Jie Yu; Hsin-Yu Huang; Ya-Lin Chang; Virginia N Lehman; Fitz Gerald S Silao; Ursela G Bigol; Alice Alma C Bungay; Anna Averette; Joseph Heitman
Journal:  Eukaryot Cell       Date:  2014-01-17

3.  Aging: an emergent phenotypic trait that contributes to the virulence of Cryptococcus neoformans.

Authors:  Tejas Bouklas; Bettina C Fries
Journal:  Future Microbiol       Date:  2015       Impact factor: 3.165

4.  A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

Authors:  Rajendra Upadhya; Woei C Lam; Brian T Maybruck; Maureen J Donlin; Andrew L Chang; Sarah Kayode; Kate L Ormerod; James A Fraser; Tamara L Doering; Jennifer K Lodge
Journal:  Fungal Genet Biol       Date:  2017-09-12       Impact factor: 3.495

Review 5.  The Cryptococcus neoformans capsule: a sword and a shield.

Authors:  Teresa R O'Meara; J Andrew Alspaugh
Journal:  Clin Microbiol Rev       Date:  2012-07       Impact factor: 26.132

6.  The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host.

Authors:  Teresa R O'Meara; Wenjie Xu; Kyla M Selvig; Matthew J O'Meara; Aaron P Mitchell; J Andrew Alspaugh
Journal:  Mol Cell Biol       Date:  2013-12-09       Impact factor: 4.272

7.  Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly.

Authors:  Pardeep Kumar; Christian Heiss; Felipe H Santiago-Tirado; Ian Black; Parastoo Azadi; Tamara L Doering
Journal:  Eukaryot Cell       Date:  2014-02-28

Review 8.  Cryptococcal Disease in HIV-Infected Children.

Authors:  Carol Kao; David L Goldman
Journal:  Curr Infect Dis Rep       Date:  2016-09       Impact factor: 3.725

Review 9.  A Call to Arms: Quest for a Cryptococcal Vaccine.

Authors:  Marley C Caballero Van Dyke; Floyd L Wormley
Journal:  Trends Microbiol       Date:  2017-11-02       Impact factor: 17.079

Review 10.  Unraveling synthesis of the cryptococcal cell wall and capsule.

Authors:  Zhuo A Wang; Lucy X Li; Tamara L Doering
Journal:  Glycobiology       Date:  2018-10-01       Impact factor: 4.313
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.