Literature DB >> 21784934

Pseudomonas aeruginosa tssC1 links type VI secretion and biofilm-specific antibiotic resistance.

Li Zhang1, Aaron J Hinz, Jean-Paul Nadeau, Thien-Fah Mah.   

Abstract

Biofilm-specific antibiotic resistance is influenced by multiple factors. We demonstrated that Pseudomonas aeruginosa tssC1, a gene implicated in type VI secretion (T6S), is important for resistance of biofilms to a subset of antibiotics. We showed that tssC1 expression is induced in biofilms and confirmed that tssC1 is required for T6S.

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Year:  2011        PMID: 21784934      PMCID: PMC3187457          DOI: 10.1128/JB.00268-11

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


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