| Literature DB >> 21784068 |
Beatrice Nico1, Domenico Ribatti.
Abstract
The aquaporins (AQPs) are a family of transmembrane water channel proteins widely distributed and play a major role in transcellular and transepithelial water movement. Moreover, recent evidence indicates that AQPs may be involved in cell migration, angiogenesis, and tumor growth. This review article summarizes literature data concerning the involvement of AQP-1 and -4 in human brain tumor growth and edema formation and suggests a potential therapeutic approach by antagonizing their biological activity.Entities:
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Year: 2011 PMID： 21784068 DOI： 10.1016/j.yexcr.2011.07.006
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905