Literature DB >> 21783748

Nitrate and nitrite concentrations in rabbit saliva Comparison with rat saliva.

S Djekoun-Bensoltane1, M Kammerer, M Larhantec, N Pilet, C Thorin.   

Abstract

The purpose of this work was to investigate the interest of rabbits for studying pharmacology and toxicology of dietary nitrate. Twenty-one females were given 1, 300 and 600mg/l nitrate in drinking water for 11 weeks. Saliva and blood were analysed for nitrate/nitrite. There is a linear relationship between the amounts of nitrate ingested and amount of nitrate in saliva, contrary to what is observed in rats. However, salivary nitrite concentrations remain low, and nitrate reductase activity in the oral cavity of the rabbit seems very weak.
Copyright © 2006 Elsevier B.V. All rights reserved.

Entities:  

Year:  2006        PMID： 21783748     DOI： 10.1016/j.etap.2006.07.007

Source DB:  PubMed          Journal:  Environ Toxicol Pharmacol        ISSN： 1382-6689            Impact factor:   4.860


  4 in total

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Authors:  Lizheng Qin; Xibao Liu; Qifei Sun; Zhipeng Fan; Dengsheng Xia; Gang Ding; Hwei Ling Ong; David Adams; William A Gahl; Changyu Zheng; Senrong Qi; Luyuan Jin; Chunmei Zhang; Liankun Gu; Junqi He; Dajun Deng; Indu S Ambudkar; Songlin Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-09       Impact factor: 11.205

2.  Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.

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Journal:  Nutr Cancer       Date:  2013       Impact factor: 2.900

3.  Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research.

Authors:  Marcelo F Montenegro; Michaela L Sundqvist; Carina Nihlén; Michael Hezel; Mattias Carlström; Eddie Weitzberg; Jon O Lundberg
Journal:  Redox Biol       Date:  2016-10-25       Impact factor: 11.799

4.  Beneficial Effects of Dietary Nitrite on a Model of Nonalcoholic Steatohepatitis Induced by High-Fat/High-Cholesterol Diets in SHRSP5/Dmcr Rats: A Preliminary Study.

Authors:  Kunihiro Sonoda; Yuka Kono; Kazuya Kitamori; Kazuo Ohtake; Sachiko Shiba; Keizo Kasono; Jun Kobayashi
Journal:  Int J Mol Sci       Date:  2022-03-08       Impact factor: 5.923
  4 in total

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