Literature DB >> 21783031

Gene regulation: piecing together the puzzle of enhancer evolution.

Rhea R Datta1, Stephen Small.   

Abstract

The sequences of some gene regulatory elements diverge considerably, even between closely related species. A detailed analysis of the fast-evolving sparkling enhancer in Drosophila now identifies key compensatory mechanisms and 'grammar' elements that are critical for maintaining functional integrity.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21783031     DOI： 10.1016/j.cub.2011.06.026

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  3 in total

1.  Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.

Authors:  Miki Fujioka; Brian Gebelein; Zenobia C Cofer; Richard S Mann; James B Jaynes
Journal:  Dev Biol       Date:  2012-04-20       Impact factor: 3.582

2.  cis-regulatory analysis of the Drosophila pdm locus reveals a diversity of neural enhancers.

Authors:  Jermaine Ross; Alexander Kuzin; Thomas Brody; Ward F Odenwald
Journal:  BMC Genomics       Date:  2015-09-16       Impact factor: 3.969

3.  Functionally conserved enhancers with divergent sequences in distant vertebrates.

Authors:  Song Yang; Nir Oksenberg; Sachiko Takayama; Seok-Jin Heo; Alexander Poliakov; Nadav Ahituv; Inna Dubchak; Dario Boffelli
Journal:  BMC Genomics       Date:  2015-10-30       Impact factor: 3.969
  3 in total

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