| Literature DB >> 21782798 |
Ming-Hui Yang1, Pei-Yu Chu, Sharon Chia-Ju Chen, Tze-Wen Chung, Wen-Cheng Chen, Lia-Beng Tan, Wei-Chih Kan, Hsien-Yi Wang, Shih-Bin Su, Yu-Chang Tyan.
Abstract
Human urine contains a large number of proteins and peptides (the urinary proteome). Global analysis of the human urinary proteome is important for understanding urinary tract diseases. Bladder cancer is the most common urological cancer with higher incidence rates in endemic areas of Blackfoot disease (BFD) in southern Taiwan. The aim of this study was to use the proteomic approach to establish urinary protein biomarkers of bladder cancer. ADAM28, identified by proteomic approaches and confirmed by Western blotting, showed significant differences compared with normal individuals, so it may be a biomarker of bladder cancer.Entities:
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Year: 2011 PMID： 21782798 DOI： 10.1016/j.bbrc.2011.07.010
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575