OBJECTIVE: To report a case of a successful pregnancy and delivery of a patient with 46,XY pure gonadal dysgenesis (Swyer syndrome) and preexisting chronic hypertension who underwent in vitro fertilization (IVF) and embryo transfer (ET). DESIGN: Case report and review of the literature. SETTING: 2nd Department of Obstetrics and Gynecology, University of Athens, Medical School, "Aretaieion" Hospital. Division of Pediatric-Adolescent Gynecology and Reconstructive Surgery. PATIENT(S): A 35-year-old woman with Swyer syndrome and chronic idiopathic hypertension. INTERVENTION(S): Karyotype analysis due to primary amenorrhea; gonadectomy, hormone therapy, investigation of hypertension, IVF using donor oocytes, embryo transfer and caesarean delivery for fetal distress. MAIN OUTCOME MEASURE(S): Successful pregnancy and live birth. RESULT(S): We present a rare case of a successful pregnancy of a patient with Swyer syndrome accompanied by idiopathic chronic hypertension. CONCLUSION(S): A woman with Swyer syndrome, hypoplastic uterus, and chronic hypertension delivered a healthy newborn.
OBJECTIVE: To report a case of a successful pregnancy and delivery of a patient with 46,XY pure gonadal dysgenesis (Swyer syndrome) and preexisting chronic hypertension who underwent in vitro fertilization (IVF) and embryo transfer (ET). DESIGN: Case report and review of the literature. SETTING: 2nd Department of Obstetrics and Gynecology, University of Athens, Medical School, "Aretaieion" Hospital. Division of Pediatric-Adolescent Gynecology and Reconstructive Surgery. PATIENT(S): A 35-year-old woman with Swyer syndrome and chronic idiopathic hypertension. INTERVENTION(S): Karyotype analysis due to primary amenorrhea; gonadectomy, hormone therapy, investigation of hypertension, IVF using donor oocytes, embryo transfer and caesarean delivery for fetal distress. MAIN OUTCOME MEASURE(S): Successful pregnancy and live birth. RESULT(S): We present a rare case of a successful pregnancy of a patient with Swyer syndrome accompanied by idiopathic chronic hypertension. CONCLUSION(S): A woman with Swyer syndrome, hypoplastic uterus, and chronic hypertension delivered a healthy newborn.
Authors: Izabela Winkler; Ilona Jaszczuk; Marek Gogacz; Piotr Szkodziak; Tomasz Paszkowski; Katarzyna Skorupska; Michał Ciebiera; Maciej Skrzypczak Journal: Int J Environ Res Public Health Date: 2022-04-20 Impact factor: 4.614