Literature DB >> 217814

Isolation of the globular region of the subcomponent q of the C1 component of complement.

E P Pâques, R Huber, H Priess, J K Wright.   

Abstract

Digestion after heat treatment of the subcomponent q of the C1 component of complement by collagenase leads to the isolation of the globular region of the protein. This product ('heads') is composed of three chains giving an overall molecular weight of about 57000. About half of the collagen-like region present in C1 q is lost after digestion. The 'heads' are shown to be soluble and hemolytically active products.

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Year:  1979        PMID： 217814     DOI： 10.1515/bchm2.1979.360.1.177

Source DB:  PubMed          Journal:  Hoppe Seylers Z Physiol Chem        ISSN： 0018-4888


  13 in total

1.  Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis.

Authors:  Kaisa E Happonen; Tore Saxne; Anders Aspberg; Matthias Mörgelin; Dick Heinegård; Anna M Blom
Journal:  Arthritis Rheum       Date:  2010-12

2.  Annexin A2 and A5 serve as new ligands for C1q on apoptotic cells.

Authors:  Myriam Martin; Jonatan Leffler; Anna M Blom
Journal:  J Biol Chem       Date:  2012-08-09       Impact factor: 5.157

3.  C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms.

Authors:  L E Leigh; B Ghebrehiwet; T P Perera; I N Bird; P Strong; U Kishore; K B Reid; P Eggleton
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

4.  Release of calreticulin from neutrophils may alter C1q-mediated immune functions.

Authors:  U Kishore; R D Sontheimer; K N Sastry; K S Zaner; E G Zappi; G R Hughes; M A Khamashta; P Strong; K B Reid; P Eggleton
Journal:  Biochem J       Date:  1997-03-01       Impact factor: 3.857

5.  Molecular modelling of human complement subcomponent C1q and its complex with C1r2C1s2 derived from neutron-scattering curves and hydrodynamic properties.

Authors:  S J Perkins
Journal:  Biochem J       Date:  1985-05-15       Impact factor: 3.857

6.  Interaction between complement subcomponent C1q and the Klebsiella pneumoniae porin OmpK36.

Authors:  S Albertí; G Marqués; S Hernández-Allés; X Rubires; J M Tomás; F Vivanco; V J Benedí
Journal:  Infect Immun       Date:  1996-11       Impact factor: 3.441

7.  Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement.

Authors:  K B Reid; J Gagnon; J Frampton
Journal:  Biochem J       Date:  1982-06-01       Impact factor: 3.857

8.  Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q.

Authors:  E H Rehmus; B M Greene; B A Everson; O D Ratnoff
Journal:  J Clin Invest       Date:  1987-08       Impact factor: 14.808

9.  Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.

Authors:  Jonatan Sjölander; Gunilla T Westermark; Erik Renström; Anna M Blom
Journal:  J Biol Chem       Date:  2012-02-13       Impact factor: 5.157

10.  Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.

Authors:  Andreas P Sjöberg; Gavin A Manderson; Matthias Mörgelin; Anthony J Day; Dick Heinegård; Anna M Blom
Journal:  Mol Immunol       Date:  2008-10-29       Impact factor: 4.407
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