PURPOSE: To evaluate the role of abdominal susceptibility-weighted imaging (SWI) in the detection of siderotic nodules in cirrhotic liver. MATERIALS AND METHODS: Forty patients with pathologically identified liver cirrhosis and 40 age/sex-matched normal controls underwent T1-, T2-, T2*-weighted imaging and SWI at 3T. Two radiologists prospectively analyzed all magnetic resonance imaging (MRI) studies. Siderotic nodules detected by each imaging technique were counted for comparison. The conspicuity of siderotic nodules was assessed using a scale from 1 to 3 (1, weak; 2, moderate; 3, prominent). RESULTS: The number of siderotic nodules detected by SWI (3863) was significantly greater than that of T1-weighted imaging (262, P < 0.001), T2-weighted imaging (842, P < 0.001), and T2*-weighted imaging (2475, P < 0.001). No suspected siderotic nodules were detected in normal controls by any imaging technique. CONCLUSION: SWI appears to provide the most sensitive method to detect siderotic nodules in cirrhotic liver.
PURPOSE: To evaluate the role of abdominal susceptibility-weighted imaging (SWI) in the detection of siderotic nodules in cirrhotic liver. MATERIALS AND METHODS: Forty patients with pathologically identified liver cirrhosis and 40 age/sex-matched normal controls underwent T1-, T2-, T2*-weighted imaging and SWI at 3T. Two radiologists prospectively analyzed all magnetic resonance imaging (MRI) studies. Siderotic nodules detected by each imaging technique were counted for comparison. The conspicuity of siderotic nodules was assessed using a scale from 1 to 3 (1, weak; 2, moderate; 3, prominent). RESULTS: The number of siderotic nodules detected by SWI (3863) was significantly greater than that of T1-weighted imaging (262, P < 0.001), T2-weighted imaging (842, P < 0.001), and T2*-weighted imaging (2475, P < 0.001). No suspected siderotic nodules were detected in normal controls by any imaging technique. CONCLUSION: SWI appears to provide the most sensitive method to detect siderotic nodules in cirrhotic liver.
Authors: Shi-Xin Chang; Guan-Wu Li; Yao Chen; Hong Bao; Lei Zhou; Jun Yuan; Dong-Mei Wu; Yong-Ming Dai Journal: PLoS One Date: 2013-06-14 Impact factor: 3.240
Authors: Wei Xing; Xiaozhou He; Mohammad A Kassir; Jie Chen; Jiule Ding; Jun Sun; Jiani Hu; Zishu Zhang; E Mark Haacke; Yongming Dai Journal: PLoS One Date: 2013-02-25 Impact factor: 3.240
Authors: Jie Chen; Jiule Ding; Yongming Dai; Wei Xing; Jun Sun; Zishu Zhang; Yang Xuan; Vasuki Pilli; E Mark Haacke; Jiani Hu Journal: PLoS One Date: 2013-06-06 Impact factor: 3.240